Levine A B
Department of Obstetrics and Gynecology, Jefferson Medical College, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.
J Reprod Med. 1998 Aug;43(8):691-2.
Optimal glycemic control prior to and during early pregnancy is essential in diabetic women.
Two cases of fetal anencephaly occurred in diabetic women who conceived with medical technical assistance but did not receive preconception counseling. Both women had poor glycemic control periconceptually, as evidenced by elevated glycosylated hemoglobin determinations in the early first trimester. Targeted sonographic evaluations in the second trimester revealed both fetuses to be anencephalic. Both women terminated their pregnancies.
Women with diabetes should be encouraged to seek preconceptual counseling and achieve tight glycemic control prior to attempting pregnancy. Health care providers play a vital role in stressing the importance of preconception care to these patients.
糖尿病女性在孕前期及孕早期实现最佳血糖控制至关重要。
两名糖尿病女性在接受医疗技术辅助受孕时未接受孕前咨询,均发生了胎儿无脑畸形。两名女性在受孕前后血糖控制不佳,孕早期糖化血红蛋白测定值升高即为证据。孕中期的针对性超声评估显示,两名胎儿均为无脑儿。两名女性均终止了妊娠。
应鼓励糖尿病女性在尝试怀孕前寻求孕前咨询并实现严格的血糖控制。医疗保健提供者在向这些患者强调孕前保健的重要性方面发挥着至关重要的作用。