Kuntz C A, Asselin T L, Dernell W S, Powers B E, Straw R C, Withrow S J
Department of Clinical Sciences, Colorado State University, Fort Collins, USA.
Vet Surg. 1998 Sep-Oct;27(5):417-22. doi: 10.1111/j.1532-950x.1998.tb00150.x.
To describe function and identify factors that affect outcome in dogs undergoing limb salvage surgery for osteosarcoma (OS) of the proximal humerus.
A retrospective study of dogs in which OS of the proximal humerus was treated with limb salvage surgery.
17 client-owned dogs.
Records were analyzed for functional outcome, recurrence, metastasis, and survival.
Outcome was good to excellent in 12% of dogs. Recurrence, metastasis, and survival were significantly affected by completeness of surgical margins. Double plating of the distal allograft-host junction significantly reduced frequency of biomechanical failure.
Limb salvage surgery for OS of the proximal humerus did not result in acceptable function and was fraught with postoperative complications. Outcome was significantly affected by completeness of surgical margins.
Limb salvage surgery for OS of the proximal humerus in dogs cannot be recommended until improvement in functional outcome and reduction in postoperative complications can be achieved. The dependence of outcome on completeness of surgical margins supports aggressive en bloc resection and marking and evaluating surgical margins.
描述对患有肱骨近端骨肉瘤（OS）的犬只进行保肢手术的功能，并确定影响手术结果的因素。
对接受肱骨近端骨肉瘤保肢手术的犬只进行回顾性研究。
17只客户拥有的犬只。
分析记录的功能结果、复发、转移和存活情况。
12%的犬只手术结果良好至优秀。手术切缘的完整性对复发、转移和存活有显著影响。异体骨远端与宿主交界处的双钢板固定显著降低了生物力学失败的发生率。
肱骨近端骨肉瘤的保肢手术未能带来可接受的功能，且术后并发症频发。手术切缘的完整性对手术结果有显著影响。
在功能结果得到改善且术后并发症减少之前，不建议对犬只的肱骨近端骨肉瘤进行保肢手术。手术结果对手术切缘完整性的依赖性支持进行积极的整块切除以及标记和评估手术切缘。
