Yin C S, Wei R Y, Chao T C, Chan C C
Department of Obstetrics and Gynecology, Buddhist Tzu-Chi College of Medicine, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan.
Int J Gynaecol Obstet. 1998 Aug;62(2):167-72. doi: 10.1016/s0020-7292(98)00061-7.
To study the effectiveness of endometrial ablation by hysteroscopic resection without prior medical preparation for the treatment of women with persistent menorrhagia.
From January 1996 to January 1997, a total of 170 women with persistent menorrhagia and/or dysmenorrhea and who underwent hysteroscopic endometrial resection were included in the study. A thorough suction curettage was done before the procedure. The operation was conducted through a continuous flow hysteroscopic resectoscope with electrosurgery while the patient was under intravenous general anesthesia. The distention fluid used was 5% dextrose with a gravity feed infusion system consisting of a 2-1 bag between 1 and 1.5 m above the uterine cavity. After the procedure, the patients' conditions were followed for at least 6-18 months by telephone interview or at our clinic.
A total of 127 women were available for a follow-up period of at least 6 months. Operative complications were 3%; three women had fever and received oral antibiotics; no uterine perforation occurred; one case of post-operative bleeding was controlled by intrauterine balloon inflation; the average operation time was 21 min; The mean fluid deficit was 435 ml. Ninety-nine out of 127 women (78%) had adequately controlled menorrhagia (18.1% had amenorrhea, 42.5% hypomenorrhea and 17.3% had normal menstrual flow), while 27 women (21.2%) were failed due to unchanged or heavier menstrual flow after surgery. Eleven (40%) out of the 27 failed cases had myoma with menorrhagia, whereas only five women (5%) out of the 99 adequately treated women had myomas (P < 0.05). Thirty-eight (54%) out of the 70 women with severe dysmenorrhea reported either lessening dysmenorrhea or no dysmenorrhea after the surgery. A total of 76 women (60%) were satisfied with the procedure. A second surgical procedure, either a resection or hysterectomy, was necessary in 13 women (10%) after ablation (seven received repeated ablations and six underwent hysterectomy).
Endometrial ablation without endometrial suppression is a cheap, effective and acceptable procedure for treatment in women with persisted persistent menorrhagia.
研究在未进行术前药物准备的情况下,经宫腔镜切除术进行子宫内膜去除术治疗持续性月经过多女性的有效性。
1996年1月至1997年1月,共有170例患有持续性月经过多和/或痛经且接受了宫腔镜子宫内膜切除术的女性纳入本研究。术前进行了彻底的吸刮术。手术在患者静脉全身麻醉下,通过带有电外科设备的连续流动宫腔镜切除镜进行。所用的膨宫液是5%葡萄糖,采用重力输注系统,由一个位于子宫腔上方1至1.5米处的2升袋组成。术后,通过电话随访或在本诊所对患者情况进行至少6至18个月的跟踪。
共有127名女性接受了至少6个月的随访。手术并发症发生率为3%;3名女性发热并接受了口服抗生素治疗;未发生子宫穿孔;1例术后出血通过宫腔内球囊充盈得以控制;平均手术时间为21分钟;平均液体丢失量为435毫升。127名女性中有99名(78%)月经过多得到了充分控制(18.1%闭经,42.5%月经过少,17.3%月经流量正常),而27名女性(21.2%)手术失败,原因是术后月经流量未改变或增多。27例失败病例中有11例(40%)患有子宫肌瘤伴月经过多,而99例治疗充分的女性中只有5例(5%)患有子宫肌瘤(P<0.05)。70例严重痛经的女性中有38例(54%)报告术后痛经减轻或无痛经。共有76名女性(60%)对该手术满意。13名女性(10%)在子宫内膜去除术后需要进行第二次手术,要么是切除术,要么是子宫切除术(7名接受了重复子宫内膜去除术,6名接受了子宫切除术)。
不进行子宫内膜预处理的子宫内膜去除术是治疗持续性月经过多女性的一种廉价、有效且可接受的方法。