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肺母细胞瘤:光镜与电镜研究

Pulmonary blastoma: A light and electron microscopic study.

作者信息

McCann M P, Fu Y S, Kay S

出版信息

Cancer. 1976 Aug;38(2):789-97. doi: 10.1002/1097-0142(197608)38:2<789::aid-cncr2820380222>3.0.co;2-3.

Abstract

A case of pulmonary blastoma studied with the electron microscope showed two distinct cell types, i.e., epithelial and mesenchymal elements. The former demonstrates the differentiation toward ciliated bronchial cells, and the latter, cartilage. In view of these findings, coupled with the current understanding of pulmonary morphogenesis, the pulmonary blastoma is more likely to be a carcinosarcoma than a true blastoma. However, the separation between pulmonary blastoma as usually employed and the so-called pulmonary carcinosarcoma seems to be desirable because of different clinicopathologic features.

摘要

一例经电子显微镜研究的肺母细胞瘤显示出两种不同的细胞类型,即上皮细胞和间充质成分。前者表现出向纤毛支气管细胞的分化,后者表现出向软骨的分化。鉴于这些发现,结合目前对肺形态发生的认识,肺母细胞瘤更可能是一种癌肉瘤而非真正的母细胞瘤。然而,由于临床病理特征不同,区分通常所说的肺母细胞瘤和所谓的肺癌肉瘤似乎是有必要的。

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