Regezi J A, Courtney R M, Kerr D A
Cancer. 1976 Aug;38(2):994-1000. doi: 10.1002/1097-0142(197608)38:2<994::aid-cncr2820380251>3.0.co;2-b.
Management of patients irradiated for oral cancer should include consideration of their oral health prior to, and after, radiation therapy. Data from 130 patients, followed for a period of 1 to 10 years, are presented and evaluated. The philosophy of retention and maintenance of as many teeth as possible is supported by this data. Extraction of teeth with severe periodontal disease after irradiation also proves to be a relatively safe operation. Osteoradionecrosis tends to be limited in extent and is generally well tolerated by the patient when treated conservatively. A treatment regimen is presented that significantly reduces the morbidity from therapeutic irradiation of the jaws. A comprehensive dental evaluation and follow-up plan coupled with patient cooperation are instrumental to the success of this program.
接受口腔癌放疗患者的管理应包括在放疗前及放疗后对其口腔健康状况的考量。本文呈现并评估了130例患者长达1至10年的随访数据。这些数据支持尽可能保留和维护更多牙齿的理念。放疗后拔除患有严重牙周病的牙齿也被证明是相对安全的手术。放射性骨坏死的范围往往较为局限,保守治疗时患者通常耐受性良好。本文提出了一种治疗方案,可显著降低颌骨放疗的发病率。全面的牙科评估和随访计划以及患者的配合对该方案的成功至关重要。