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多重化学物质敏感综合征

Multiple chemical sensitivity syndrome.

作者信息

Magill M K, Suruda A

机构信息

Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City 84132, USA.

出版信息

Am Fam Physician. 1998 Sep 1;58(3):721-8.

PMID:9750540
Abstract

Multiple chemical sensitivity (MCS) is a syndrome in which multiple symptoms reportedly occur with low-level chemical exposure. Several theories have been advanced to explain the cause of MCS, including allergy, toxic effects and neurobiologic sensitization. There is insufficient scientific evidence to confirm a relationship between any of these possible causes and symptoms. Patients with MCS have high rates of depression, anxiety and somatoform disorders, but it is unclear if a causal relationship or merely an association exists between MCS and psychiatric problems. Physicians should compassionately evaluate and care for patients who have this distressing condition, while avoiding the use of unproven, expensive or potentially harmful tests and treatments. The first goal of management is to establish an effective physician-patient relationship. The patient's efforts to return to work and to a normal social life should be encouraged and supported.

摘要

多重化学物质敏感症(MCS)是一种据报道在低水平化学物质暴露时会出现多种症状的综合征。已经提出了几种理论来解释MCS的病因,包括过敏、毒性作用和神经生物学致敏。没有足够的科学证据来证实这些可能的病因与症状之间的关系。MCS患者中抑郁症、焦虑症和躯体形式障碍的发生率很高,但尚不清楚MCS与精神问题之间是因果关系还是仅仅是一种关联。医生应该同情地评估和照顾患有这种痛苦病症的患者,同时避免使用未经证实、昂贵或有潜在危害的检查和治疗方法。治疗的首要目标是建立有效的医患关系。应该鼓励和支持患者努力重返工作岗位和恢复正常的社交生活。

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Multiple chemical sensitivity syndrome.多重化学物质敏感综合征
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Redox Status in Patients Suffering from Multiple Chemical Sensitivity (MCS): A Pilot Study.多重化学敏感性(MCS)患者的氧化还原状态:一项初步研究。
J Clin Med. 2025 Sep 2;14(17):6185. doi: 10.3390/jcm14176185.
2
Psychological symptoms and self-image of patients with complaints attributed to dental restorative materials.对归咎于牙科修复材料的患者的心理症状和自我形象的评估。
Clin Oral Investig. 2019 Jun;23(6):2805-2811. doi: 10.1007/s00784-018-2707-4. Epub 2018 Oct 27.
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"Struggle to obtain redress": Women's experiences of living with symptoms attributed to dental restorative materials and/or electromagnetic fields.
“争取补救”:女性在忍受归因于牙科修复材料和/或电磁场的症状下的生活经历。
Int J Qual Stud Health Well-being. 2016 Dec 9;11:32820. doi: 10.3402/qhw.v11.32820. eCollection 2016.
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Chemical intolerance in primary care settings: prevalence, comorbidity, and outcomes.基层医疗环境中的化学物质不耐受:患病率、共病和结局。
Ann Fam Med. 2012 Jul-Aug;10(4):357-65. doi: 10.1370/afm.1346.
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Drug Allergies and Childhood Trauma among Chronic Pain Patients.慢性疼痛患者中的药物过敏与童年创伤
Psychiatry (Edgmont). 2009 Jun;6(6):17-8.
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General practitioners' experiences with provision of healthcare to patients with self-reported multiple chemical sensitivity.全科医生为自我报告有多重化学敏感性的患者提供医疗服务的经历。
Scand J Prim Health Care. 2009;27(3):148-52. doi: 10.1080/02813430902888355.
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Psychobiological personality dimensions in two environmental-illness patient groups.
Clin Oral Investig. 2005 Dec;9(4):251-6. doi: 10.1007/s00784-005-0015-2. Epub 2005 Oct 8.
8
Multiple chemical sensitivity: a review of the theoretical and research literature.多重化学物质敏感症:理论与研究文献综述
Neuropsychol Rev. 2000 Dec;10(4):183-211. doi: 10.1023/a:1026460726965.