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内收性杓状软骨固定术:一种用于麻痹性发音障碍的新手术及其对植入物喉内移术的意义

Adduction arytenopexy: a new procedure for paralytic dysphonia with implications for implant medialization.

作者信息

Zeitels S M, Hochman I, Hillman R E

机构信息

Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Ann Otol Rhinol Laryngol Suppl. 1998 Sep;173:2-24.

PMID:9750545
Abstract

Arytenoid adduction was designed to enhance posterior glottal closure in patients with paralytic dysphonia by reproducing lateral cricoarytenoid muscle function. However this procedure can exaggerate normal medial rotation of the vocal process, because the agonist-antagonist function of the interarytenoid, lateral thyroarytenoid, and posterior cricoarytenoid muscles is not simulated. Therefore, a new adduction procedure (adduction arytenopexy) was devised to affix the arytenoid on the cricoid facet in a more optimal position for glottal sound production. The adduction arytenopexy procedure was designed on fresh cadavers. In this technique, the lateral aspect of the cricoarytenoid joint is opened widely and the body of the arytenoid is manually medialized along the cricoid facet. A specially designed single suture is then placed through the posterior cricoid and the body or the muscular process of the arytenoid to achieve 2-point fixation. This draws the arytenoid posteriorly, superiorly, and medially for precise positioning. The arytenoid is rocked internally on the cricoid facet, and suture tension is adjusted appropriately to simulate normal cricoarytenoid adduction. In the first study, the adduction arytenopexy was compared with the classic arytenoid adduction in 10 fresh cadaver larynges. The new arytenopexy procedure resulted in an average increase of 2.1 mm (p < .01) in the length of the musculomembranous vocal fold, whereas the classic arytenoid adduction did not reveal a significant change in length. Additionally, the adduction arytenopexy resulted in a consistently higher vocal fold and a more normally contoured arytenoid than the classic adduction procedure. The second study consisted of a clinical trial in which 12 patients, who presented with a widely patent posterior glottis, underwent adduction arytenopexy in conjunction with implant medialization. The procedure was successful in all patients, and there were minimal complications. In the third study, preoperative and postoperative vocal assessment measures (stroboscopic, aerodynamic, acoustic, and perceptual) were analyzed in 9 of the 12 patients. The most striking preoperative stroboscopic observation was that 8 of the 9 patients presented with an aperiodic vibrational flutter during phonation due to severe valvular incompetence. Postoperatively, all patients developed complete closure of the glottal chink and effective entrained oscillation of the vocal folds. This visual improvement in function was commensurate with comparable changes in most of the other objective and subjective measures of vocal function. The new adduction arytenopexy procedure closely simulates the biomechanics underlying normal glottal closure and cricoarytenoid adduction. In turn, complex implant design shapes are not necessary to achieve proper alignment of the arytenoid and the vocal fold. Because the arytenoid is properly positioned prior to the medialization, implants can be sized more precisely and are unencumbered by an anterior thyroid lamina suture. These procedural innovations resulted in enhanced entrained oscillation of the glottal valve and, in turn, improved laryngeal sound production.

摘要

杓状软骨内收术旨在通过重现环杓侧肌功能来增强麻痹性发音障碍患者的声门后联合闭合。然而,该手术可能会夸大声带突正常的内旋,因为杓间肌、甲杓侧肌和环杓后肌的拮抗肌功能未得到模拟。因此,设计了一种新的内收手术(内收杓状软骨固定术),将杓状软骨固定在环状软骨小关节面上更有利于声门发声的最佳位置。内收杓状软骨固定术是在新鲜尸体上设计的。在这项技术中,广泛切开环杓关节的外侧,然后沿环状软骨小关节面手动将杓状软骨体向内移位。接着放置一根特制的单缝线,穿过环状软骨后部以及杓状软骨体或肌突,以实现两点固定。这会将杓状软骨向后、向上和向内牵拉,以精确就位。杓状软骨在环状软骨小关节面上向内摆动,并适当调整缝线张力以模拟正常的环杓关节内收。在第一项研究中,在10个新鲜尸体喉部将内收杓状软骨固定术与经典的杓状软骨内收术进行了比较。新的杓状软骨固定术使肌膜性声带长度平均增加了2.1毫米(p <.01),而经典的杓状软骨内收术在长度上未显示出显著变化。此外,与经典内收术相比,内收杓状软骨固定术使声带始终更高,杓状软骨轮廓更正常。第二项研究包括一项临床试验,12例声门后联合广泛开放的患者接受了内收杓状软骨固定术并联合植入物内移术。该手术在所有患者中均成功,且并发症极少。在第三项研究中,对12例患者中的9例进行了术前和术后的嗓音评估测量(频闪喉镜检查、空气动力学、声学和感知评估)。术前最显著的频闪喉镜观察结果是,9例患者中有8例在发声时由于严重的瓣膜功能不全出现非周期性振动颤动。术后,所有患者的声门裂隙完全闭合,声带有效同步振动。这种功能上的视觉改善与大多数其他嗓音功能客观和主观测量的相应变化相当。新的内收杓状软骨固定术紧密模拟了正常声门闭合和环杓关节内收的生物力学原理。相应地,无需复杂的植入物设计形状来实现杓状软骨和声带的正确对齐。由于在进行内移术前杓状软骨已正确定位,植入物的尺寸可以更精确地确定,并且不受甲状腺前板缝线的影响。这些手术创新导致声门瓣膜的同步振动增强,进而改善了喉部发声。

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