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[麻醉与重症监护中的克劳德·伯纳德 - 霍纳综合征及其相反情况,普尔富尔·迪·佩蒂综合征]

[Claude Bernard-Horner syndrome and its opposite, Pourfour du Petit syndrome, in anesthesia and intensive care].

作者信息

Ségura P, Speeg-Schatz C, Wagner J M, Kern O

机构信息

Service d'anesthésie-réanimation chirurgicale, hôpital de Hautepierre, Strasbourg, France.

出版信息

Ann Fr Anesth Reanim. 1998;17(7):709-24. doi: 10.1016/s0750-7658(98)80108-1.

Abstract

OBJECTIVE

To analyse cases of Horner's syndrome (HS) and its opposite, Pourfour du Petit's syndrome (PPS), occurring in anaesthesia and intensive therapy with consideration of the data of current literature.

DATA SOURCES

For this paper we have reviewed the French, English and German literature published in anaesthesia and intensive care journals using Medline search and the current textbooks.

STUDY SELECTION

All observational studies on these syndromes, whether clinical cases or letters to the editor, form the basis for this article.

DATA EXTRACTION

The articles were analysed mainly with regard to diagnosis, therapy and prognosis of syndromes due to iatrogenic causes.

DATA SYNTHESIS

HS is caused by a paralysis of the ipsilateral sympathetic cervical chain and includes a ptosis of the upper eyelid, a slight elevation of the lower lid, a sinking of the eyeball, a constriction of the pupil, a narowing of the palpebral fissure, a nasal stuffiness associated with anhidrosis, and flushing of the affected side of the face. Regional anaesthesia (intra-oral anaesthesia, brachial plexus block, epidural anaesthesia whether by thoracic, lumbar or caudal approach, as well as interpleural analgesia) is the main anaesthetic cause for HS. HS due to the effect of a local anaesthetic is transient, it can precede a high spinal block and a cardiovascular collapse. HS from puncture of the internal jugular vein is most often permanent. When transient, HS regresses within 3 months after puncture. Other causes of HS include intraoperative posture, pleural drain, neck surgery, neck trauma. A mydriatic collyrium, such as phenylephrine, resolves ptosis for less than 1 hour and results in blurred vision from pupillary dilation. Major ptosis requires surgery. PPS is the reciprocal HS and is caused by a stimulation of the ipsilateral sympathetic cervical chain. PPS can precede HS. It carries a risk for conjunctivitis, keratitis and epiphora in case of major exophthalmia. PPS is often reported as an unilateral mydriasis. PPS has the same causes as HS. Myotic collyriums are relatively inefficient. Major lid retraction requires a tarsorraphy, pomades and nocturnal lid occlusion. A part of HS and most PPS occurring in anaesthesia and intensive care remain unrecognized or are recognized with delay, especially if they remain minor and transient or when they occur in unconscious patients, in horizontal posture.

摘要

目的

结合当前文献数据,分析麻醉和重症治疗中出现的霍纳综合征(HS)及其相反情况,即普尔富尔·迪·佩蒂综合征(PPS)的病例。

数据来源

本文通过医学在线搜索以及当前教科书,对麻醉和重症监护期刊上发表的法语、英语和德语文献进行了综述。

研究选择

所有关于这些综合征的观察性研究,无论是临床病例还是致编辑信,均构成本文的基础。

数据提取

主要针对医源性病因所致综合征的诊断、治疗和预后对文章进行分析。

数据综合

HS由同侧颈交感神经链麻痹引起,包括上睑下垂、下睑轻度上抬、眼球内陷、瞳孔缩小、睑裂变窄、伴有无汗的鼻充血以及患侧面部潮红。区域麻醉(口腔内麻醉、臂丛神经阻滞、硬膜外麻醉,无论是经胸段、腰段还是骶管途径,以及胸膜间镇痛)是HS的主要麻醉原因。局部麻醉作用所致的HS是短暂的,可先于高位脊髓阻滞和心血管虚脱出现。颈内静脉穿刺引起的HS大多是永久性的。若是短暂性的,HS在穿刺后3个月内消退。HS的其他原因包括术中体位、胸腔引流、颈部手术、颈部创伤。散瞳眼膏,如去氧肾上腺素,可使上睑下垂缓解不到1小时,并因瞳孔散大导致视力模糊。严重上睑下垂需要手术治疗。PPS与HS相反,由同侧颈交感神经链受刺激引起。PPS可先于HS出现。严重眼球突出时,有发生结膜炎、角膜炎和溢泪的风险。PPS常被报告为单侧瞳孔散大。PPS与HS病因相同。缩瞳眼膏效果相对不佳。严重眼睑退缩需要睑缘缝合术、药膏和夜间眼睑遮盖。麻醉和重症监护中出现的部分HS和大多数PPS未被识别或延迟识别,特别是当它们症状轻微且短暂,或发生在无意识患者处于平卧位时。

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