Larsen D K, Asmundson G J, Stein M B
Clinical Research and Development Program, Regina Health District, Saskatchewan, Canada.
Depress Anxiety. 1998;8(1):24-8.
Several studies have found higher resting heart rate among patients with panic disorder compared to healthy controls, whereas others have found no differences. It has been suggested that these differences may result from anticipatory anxiety. The purpose of this study was to compare the resting heart rates of 10 patients with panic disorder, 11 patients with social phobia, and 13 healthy controls during two consecutive visits to our laboratory. There were no significant differences between groups on resting heart rate on either day. However, patients with panic disorder did have significantly higher resting heart rates on day 1 versus day 2. This suggests that patients with panic disorder may experience greater anticipatory anxiety which is manifested in a higher resting heart rate than patients with social phobia or healthy controls. Implications for previous and future reports on resting heart rate measures in patients with panic disorder are discussed.
多项研究发现，与健康对照组相比，惊恐障碍患者的静息心率更高，而其他研究则未发现差异。有人认为，这些差异可能源于预期性焦虑。本研究的目的是比较10名惊恐障碍患者、11名社交恐惧症患者和13名健康对照者在连续两次到我们实验室就诊期间的静息心率。两组在任何一天的静息心率均无显著差异。然而，惊恐障碍患者在第1天的静息心率明显高于第2天。这表明，惊恐障碍患者可能经历更大的预期性焦虑，这表现为比社交恐惧症患者或健康对照者更高的静息心率。本文讨论了既往及未来关于惊恐障碍患者静息心率测量报告的意义。
