Schatte E C, Hirshberg S J, Fallick M L, Lipschultz L I, Kim E D
Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA.
J Urol. 1998 Oct;160(4):1338-40.
We prospectively examined the effect of varicocelectomy on standard semen parameters and Kruger strict morphology, including site of specific sperm defect.
Kruger strict morphology and routine semen analysis were performed in a blinded fashion before and a minimum of 4 months after varicocelectomy in 61 subfertile men with a primary diagnosis of varicocele.
Sperm motility, total number of motile sperm, and percentage and total number of sperm with normal strict morphology were significantly increased after varicocele repair. Average density was also increased, while volume and forward progression were unchanged. The percentage of normal head strict morphology was significantly improved, whereas tail and neck morphology did not reflect similar changes.
Varicocele repair in subfertile men improves Kruger strict morphology. In addition, motility and total motile sperm are significantly improved after repair. Since the stoichiometry of the sperm head is crucial to egg and sperm interaction, this decrease in head defects may be partially responsible for the increase in pregnancy rates after varicocele repair.
我们前瞻性地研究了精索静脉曲张切除术对标准精液参数和克鲁格严格形态学的影响，包括特定精子缺陷的部位。
对61例初步诊断为精索静脉曲张的不育男性，在精索静脉曲张切除术前及术后至少4个月，以盲法进行克鲁格严格形态学检查和常规精液分析。
精索静脉曲张修复术后，精子活力、活动精子总数、具有正常严格形态的精子百分比及总数均显著增加。平均密度也增加，而精液量和向前运动能力未改变。头部正常严格形态的百分比显著改善，而尾部和颈部形态未显示类似变化。
不育男性的精索静脉曲张修复术可改善克鲁格严格形态学。此外，修复术后活力和活动精子总数显著提高。由于精子头部的化学计量对卵子与精子相互作用至关重要，头部缺陷的减少可能部分解释了精索静脉曲张修复术后妊娠率的增加。
