Stegemann J
Cardiology. 1976;61 suppl 1:255-66. doi: 10.1159/000169816.
Investigations on orthostatic tolerance and physical fitness prior to and after 6-8 h immersion experiments surprisingly revealed that all untrained subjects endured pre- and postimmersion tilt table tests without subjective complaints, whereas after immersion all trained participants collapsed within the first minutes of erect position displaying symptoms of a vasovagal syncope. Assuming that this impaired orthostatic tolerance of trained subjects can partially be referred to influences of an altered blood pressure control system we decided to record the blood pressure characteristics of both groups. Thereby, the transmural pressure of the carotid artery was changed by applying from outside either reduced or exceeding pressures. The controller sensitivity in the untrained group was almost twice as high as in the trained one. This implies a better regulatory response to disturbing interference in the untrained. Under normal conditions the controlling capacity of both groups is sufficient to cope with body position changes. However, during stress situations--in this case, reduction of aldosterone concentration as well as losses of plasma volume due to the 'Gauer-Henry-Reflex'--blood pressure regulation first fails in the trained subjects.
在6 - 8小时浸泡实验前后对直立耐力和身体素质进行的调查意外发现,所有未经训练的受试者在浸泡前后的倾斜台测试中均无主观不适,而浸泡后所有训练有素的参与者在直立姿势的最初几分钟内就出现血管迷走性晕厥症状而瘫倒。假设训练有素的受试者这种受损的直立耐力部分可归因于血压控制系统改变的影响,我们决定记录两组的血压特征。由此,通过从外部施加降低或超过的压力来改变颈动脉的跨壁压力。未经训练组的控制器敏感性几乎是训练组的两倍。这意味着未经训练者对干扰的调节反应更好。在正常情况下,两组的控制能力足以应对体位变化。然而,在应激情况下——在本案例中,由于“高尔-亨利反射”导致醛固酮浓度降低以及血浆容量流失——血压调节首先在训练有素的受试者中失效。