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[腹腔镜下Thal胃底折叠术治疗儿童胃食管反流的良好效果]

[Good results of laparoscopic Thal fundoplication for treatment of gastroesophageal reflux in children].

作者信息

Arends N J, Bax N M, van der Zee D C

机构信息

Wilhelmina Kinderziekenhuis, afd. Kinderchirurgie, Utrecht.

出版信息

Ned Tijdschr Geneeskd. 1998 Jun 6;142(23):1321-4.

PMID:9752038
Abstract

OBJECTIVE

Evaluation of the results of laparoscopic fundoplication according to Thal as a treatment for gastro-oesophageal reflux in children.

DESIGN

Prospective, descriptive.

SETTING

Department of paediatric surgery, Wilhelmina Children's Hospital, Utrecht, the Netherlands.

METHODS

Between November 1993 and May 1996, 53 children with reflux and an average age of 6 years underwent laparoscopic fundoplication according to Thal; in 23 of them a gastrostomy was created as well. The most important symptoms were vomiting and lack of growth. There were 18 children with primary reflux and 35 with secondary reflux, 28 of whom had psychomotor retardation. Preoperatively all patients were subjected to 24-hour oesophageal pH-monitoring, upper GI series and oesophagogastroscopy. Pathological reflux was defined as a pH < 4 during 5% or more of the total time measured (24 hours). pH-monitoring was repeated three months postoperatively to evaluate the effect of the fundoplication and esophagogastroscopy was repeated in case of preoperative oesophagitis.

RESULTS

In one patient the laparoscopic approach was converted peroperatively because of bleeding that had stopped on exploration. Enteral feeding could be recommenced on day one in 49 of 53 children. The mean hospitalisation time was 4.4 days. One patient was reoperated for a too tight fundoplication and two patients died of unrelated causes. The mean follow-up period for the other 50 patients was 11 months (1-35). On follow-up, 42 of them (84%) were free of symptoms, while 31 of 41 children (76%) in whom pH-monitoring could be done 3 months postoperatively displayed no recurrence of pathological reflux.

CONCLUSION

Thal fundoplication can be performed laparoscopically in children. Enteral feeding becomes possible again quickly and the period of hospitalisation is short.

摘要

目的

评估采用塔尔(Thal)术式行腹腔镜胃底折叠术治疗儿童胃食管反流的效果。

设计

前瞻性描述性研究。

地点

荷兰乌得勒支市威廉明娜儿童医院小儿外科。

方法

1993年11月至1996年5月,53例平均年龄6岁的反流患儿接受了塔尔术式的腹腔镜胃底折叠术;其中23例同时行了胃造口术。最主要的症状是呕吐和生长发育迟缓。原发性反流患儿18例,继发性反流患儿35例,其中28例有精神运动发育迟缓。所有患者术前均接受24小时食管pH监测、上消化道造影及食管胃镜检查。病理性反流定义为在测量的总时间(24小时)的5%或更多时间内pH值<4。术后3个月重复pH监测以评估胃底折叠术的效果,术前有食管炎的患者重复食管胃镜检查。

结果

1例患者术中因探查时出血停止而将腹腔镜手术转为开腹手术。53例患儿中有49例在术后第1天即可重新开始肠内喂养。平均住院时间为4.4天。1例患者因胃底折叠术过紧而再次手术,2例患者死于无关原因。其他50例患者的平均随访时间为11个月(1 - 35个月)。随访时,其中42例(84%)无症状,术后3个月可行pH监测的41例患儿中有31例(76%)未出现病理性反流复发。

结论

塔尔胃底折叠术可在儿童中通过腹腔镜进行。肠内喂养能很快重新开始,且住院时间短。

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