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[幼儿哮喘:家庭医生与儿科医生不同的治疗方法,1至2.5年症状随访]

[Asthma in young children: a different approach to treatment by the family physician vs the pediatrician, a follow-up of symptoms over a period of 1 to 2.5 years].

作者信息

Brand P L, van Aalderen W M

机构信息

Academisch Ziekenhuis, Beatrix Kinderkliniek, afd. Kinderlongziekten, Groningen.

出版信息

Ned Tijdschr Geneeskd. 1998 Jun 27;142(26):1501-4.

PMID:9752069
Abstract

OBJECTIVE

To compare the therapeutic approaches to asthmatic symptoms in young children of general practitioners and paediatric pulmonologists, and to investigate the outcome of asthma in young children.

DESIGN

Retrospective, descriptive.

SETTING

Paediatric pulmonology outpatient clinic, University Hospital, Groningen, the Netherlands.

METHOD

Charts of all 91 children younger than 2 years of age who were newly referred for recurrent cough and wheeze (asthma) between January 1, 1994, and September 30, 1995, were reviewed. Data were collected on clinical characteristics, drugs prescribed by the general practitioners, results of laboratory tests, and treatment prescribed by the paediatric pulmonologists. All children were followed up for periods of 12 to 30 months.

RESULTS

Sixty-one children (67%) had been treated with antibiotics or with oral anti-asthma drugs by their general practitioners. No child had a positive radioallergosorbent test for inhaled allergens. Paediatric pulmonologists most commonly prescribed inhaled corticosteroids and bronchodilators to these patients. After 12-30 months of follow-up, 48 patients (53%) had no further symptoms. The only factor statistically significantly related to persistence of asthmatic symptoms during follow-up was aggravation of complaints by weather influences (odds ratio: 4; 95% confidence interval: 1-12).

CONCLUSION

The common practice of prescribing antibiotics and oral anti-asthma drugs to young children in general practice is contrary to recent consensus reports on the treatment of asthma. Even in young children referred to specialists with asthmatic symptoms, such symptoms are commonly transient. Aggravation of symptoms by weather influences, which may be an expression of bronchial hyperresponsiveness, is a risk factor for persistence of symptoms.

摘要

目的

比较全科医生和儿科肺科医生对幼儿哮喘症状的治疗方法,并调查幼儿哮喘的转归情况。

设计

回顾性、描述性研究。

地点

荷兰格罗宁根大学医院儿科肺科门诊。

方法

查阅了1994年1月1日至1995年9月30日期间新转诊的91名2岁以下反复咳嗽和喘息(哮喘)患儿的病历。收集了临床特征、全科医生开具的药物、实验室检查结果以及儿科肺科医生开具的治疗方法等数据。对所有患儿进行了12至30个月的随访。

结果

61名患儿(67%)曾接受全科医生开具的抗生素或口服抗哮喘药物治疗。没有患儿吸入性变应原的放射变应原吸附试验呈阳性。儿科肺科医生最常给这些患者开具吸入性糖皮质激素和支气管扩张剂。随访12至30个月后,48名患者(53%)无进一步症状。随访期间与哮喘症状持续存在唯一有统计学显著相关性的因素是天气影响导致症状加重(优势比:4;95%置信区间:1 - 12)。

结论

全科医疗中给幼儿开具抗生素和口服抗哮喘药物的常见做法与近期关于哮喘治疗的共识报告相悖。即使是转诊至专科医生处的有哮喘症状的幼儿,这些症状通常也是短暂的。天气影响导致症状加重可能是支气管高反应性的一种表现,是症状持续存在的一个危险因素。

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