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年轻女性使用电热毯与患乳腺癌风险

Electric blanket use and breast cancer risk among younger women.

作者信息

Gammon M D, Schoenberg J B, Britton J A, Kelsey J L, Stanford J L, Malone K E, Coates R J, Brogan D J, Potischman N, Swanson C A, Brinton L A

机构信息

Division of Epidemiology, Columbia School of Public Health, New York, NY, USA.

出版信息

Am J Epidemiol. 1998 Sep 15;148(6):556-63. doi: 10.1093/oxfordjournals.aje.a009681.

Abstract

To investigate whether use of electric blankets, one of the largest sources of electromagnetic field exposure in the home, is associated with the risk of female breast cancer, the authors analyzed data from a population-based US case-control study. The 2,199 case patients were under age 55 years and had been newly diagnosed with breast cancer between 1990 and 1992. The 2,009 controls were frequency-matched to cases by 5-year age group and geographic area. There was little or no risk associated with ever having used electric blankets, mattress pads, or heated water beds among women under age 45 years (adjusted odds ratio = 1.01, 95% confidence interval 0.86-1.18) or among women aged > or =45 years (adjusted odds ratio = 1.12, 95% confidence interval 0.87-1.43). There was no substantial variation in risk with duration of use; with whether the appliance was used only to warm the bed or used throughout the night; with menopausal status; or with the cases' hormone receptor status or stage of disease. Potential breast cancer risk factors that were associated with electric blanket use did not substantially confound the associations under investigation. These data do not support the hypothesis that electric blanket use increases breast cancer risk among women under age 55 years.

摘要

为了调查家用电磁场暴露的最大来源之一——电热毯的使用是否与女性乳腺癌风险相关,作者分析了一项基于美国人群的病例对照研究的数据。2199例病例患者年龄在55岁以下,于1990年至1992年期间被新诊断为乳腺癌。2009例对照按5岁年龄组和地理区域与病例进行频率匹配。45岁以下女性或45岁及以上女性曾经使用电热毯、床垫或热水床几乎没有或没有风险(调整后的优势比=1.01,95%置信区间0.86-1.18)。风险在使用持续时间、器具是仅用于暖床还是整夜使用、绝经状态、病例的激素受体状态或疾病分期方面没有显著差异。与电热毯使用相关的潜在乳腺癌风险因素并未显著混淆所调查的关联。这些数据不支持电热毯使用会增加55岁以下女性患乳腺癌风险这一假设。

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