Dube A, Khalsa A, Gupta S K, Singh U, Sharma P
Department of Physiology, SMS Medical College, Jaipur.
Indian Heart J. 1998 May-Jun;50(3):292-4.
Serum tocopherols and lipids levels in 40 coronary artery disease patients were statistically analysed in relation to those of the normal controls and an attempt was made to define the correlation between tocopherols and various lipids. Serum tocopherols levels were found to be significantly low in coronary artery disease patients as compared to those of the controls implicating an inverse relationship between coronary artery disease and serum level of tocopherols. Coronary artery disease population did not register any significant change in various blood lipids, except triglyceride fraction, as compared to that of the normal population. Serum tocopherols and lipids were also analysed in relation to age and sex. The preliminary data suggest that coronary artery disease patients have sub-optimal tocopherols level (0.58 +/- 0.26 mg/dl) as compared to that of the normal controls (0.81 +/- 0.34 mg/dl; p < 0.001), which may be an important risk and/or contributing factor for atherogenesis and coronary artery disease
对40名冠状动脉疾病患者的血清生育酚和脂质水平与正常对照组进行了统计学分析，并试图确定生育酚与各种脂质之间的相关性。结果发现，与对照组相比，冠状动脉疾病患者的血清生育酚水平显著降低，这表明冠状动脉疾病与血清生育酚水平呈负相关。与正常人群相比，冠状动脉疾病人群除甘油三酯部分外，各种血脂均无显著变化。还对血清生育酚和脂质与年龄和性别进行了分析。初步数据表明，与正常对照组（0.81±0.34mg/dl；p<0.001）相比，冠状动脉疾病患者的生育酚水平不理想（0.58±0.26mg/dl），这可能是动脉粥样硬化和冠状动脉疾病的重要风险和/或促成因素。
