使用PMRS对小鼠成纤维细胞（NIH3T3）和纤维肉瘤细胞系（WEHI-164和MFS 8）进行表征。
Characterization of mouse fibroblast (NIH3T3) and fibrosarcoma cell lines (WEHI-164 and MFS 8) using PMRS.
作者信息
Jayashree B, Visalakshi V, Rajalakshmi K R, Sukumaran M S, Moni M S, Rajkumar T, Deshmukh S
机构信息
Biophysics Division, Cancer Institute, Madras.
出版信息
Indian J Biochem Biophys. 1998 Apr;35(2):108-14.
Proton magnetic resonance Spectroscopy (PMRS) has been used to study the differences between immortalized fibroblasts and fibrosarcoma cells of different grade. One and two dimensional purged correlation spectroscopy (PCOSY) have been used to assess intact viable fibroblast and fibrosarcoma cells, and differences in the triglyceride, cellular metabolite, and cell surface fucosylation patterns between the three cell lines have been observed. The clinical implication of this study is the potential use of PMRS as an adjunct to conventional histopathology.
质子磁共振波谱（PMRS）已被用于研究永生化成纤维细胞与不同分级的纤维肉瘤细胞之间的差异。一维和二维净化相关波谱（PCOSY）已被用于评估完整存活的成纤维细胞和纤维肉瘤细胞，并且已观察到三种细胞系之间甘油三酯、细胞代谢物和细胞表面岩藻糖基化模式的差异。这项研究的临床意义在于PMRS作为传统组织病理学辅助手段的潜在用途。
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