Kacl G M, Bruder E, Pfammatter T, Follath F, Salomon F, Debatin J F
Department of Radiology, University Hospital Zürich, Switzerland.
J Comput Assist Tomogr. 1998 Sep-Oct;22(5):687-91. doi: 10.1097/00004728-199809000-00003.
Our goal was to assess the MR appearance and histologic correlation of primary pulmonary artery angiosarcoma.
Four patients with tumorous masses in the pulmonary arteries were evaluated by dynamic contrast-enhanced MRI using T1- and T2-weighted SE images, GE images, as well as coronal 3D MRA in breath-hold technique. The percentage of tumor enhancement was determined by measuring regions of interest before and after Gd-DTPA administration on the 2D multiplanar spoiled GRE images.
All four masses showed some contrast enhancement on the dynamically acquired GRE images. The degree of contrast enhancement correlated with the degree of tumor differentiation, content of myxoid matrix, and associated thrombus. Contrast-enhanced 3D MRA was useful for preoperative delineation of the peripheral pulmonary arteries to the subsegmental order.
Dynamic contrast-enhanced 3D MRA of the pulmonary arteries can be used to delineate pulmonary arterial angiosarcomas preoperatively. Considerable variability of contrast agent uptake reflects the wide histologic behavior of these masses in differentiation from central pulmonary embolism.
我们的目标是评估原发性肺动脉血管肉瘤的磁共振成像表现及其与组织学的相关性。
对4例肺动脉内有肿瘤性肿块的患者进行动态对比增强磁共振成像评估，采用T1加权和T2加权自旋回波图像、梯度回波图像以及屏气技术下的冠状位三维磁共振血管造影。通过在二维多平面扰相梯度回波图像上测量钆喷酸葡胺给药前后的感兴趣区来确定肿瘤强化百分比。
所有4个肿块在动态采集的梯度回波图像上均显示出一定程度的对比增强。对比增强程度与肿瘤分化程度、黏液样基质含量及相关血栓有关。对比增强三维磁共振血管造影有助于术前将外周肺动脉描绘到亚段水平。
肺动脉动态对比增强三维磁共振血管造影可用于术前描绘肺动脉血管肉瘤。造影剂摄取的显著变异性反映了这些肿块与中央型肺栓塞在组织学表现上的广泛差异。
