致幻剂、触觉增进剂和兴奋剂的化学与药理学。
Chemistry and pharmacology of hallucinogens, entactogens and stimulants.
作者信息
Kovar K A
机构信息
Institute of Pharmacy, University of Tübingen, Germany.
出版信息
Pharmacopsychiatry. 1998 Jul;31 Suppl 2:69-72. doi: 10.1055/s-2007-979349.
Amphetamines, tryptamines, phencyclidines, tetrahydrocannabinol and substances of the ecstasy group are characterized as stimulants, hallucinogens and entactogens. The various effects of each group and their mode of action in different transmitter systems are described. 28 new compounds of the amphetamine and tryptamine series has been calculated, which exceed the hallucinogenic effects of mescaline. The different pathways of the metabolism of MDMA (ecstasy) and MDE in humans may probably explain their individual effects.
苯丙胺类、色胺类、苯环己哌啶、四氢大麻酚及摇头丸类物质被归类为兴奋剂、致幻剂和触觉剂。文中描述了每组物质的各种效应及其在不同递质系统中的作用方式。已计算出28种苯丙胺和色胺系列的新化合物，其致幻效果超过了三甲氧苯乙胺。人类体内3,4－亚甲基二氧甲基苯丙胺（摇头丸）和3,4－亚甲基二氧乙基苯丙胺的不同代谢途径可能解释了它们各自的效应。
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