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[使用多叶准直器产生调强射束]

[Use of a multileaf collimator for the production of intensity-modulated beams].

作者信息

Papatheodorou S, Rosenwald J C, Castellanos M E, Zefkili S, Bonvalet L, Gaboriaud G

机构信息

Service de physique médicale, institut Curie, Paris, France.

出版信息

Cancer Radiother. 1998 Jul-Aug;2(4):392-403. doi: 10.1016/s1278-3218(98)80352-1.

DOI:10.1016/s1278-3218(98)80352-1
PMID:9755754
Abstract

In external radiotherapy, the use of intensity modulated fields has been proposed for tissue and non-homogeneity compensation or for the generation of conformal dose distributions. Multileaf collimators can be employed dynamically for the modulation of the X-ray field in two dimensions. Efficient dynamic collimation became possible due to advances in computer and linear accelerator technology. It presents a number of advantages over conventional methods such as the use of compensators. We have developed a program which calculates, from a given intensity distribution, the motion of the MLC leaves as a function of monitor units, and we have applied it on a Varian linear accelerator with a 40 pair multileaf collimator. The analysis of the experimental results demonstrates the feasibility and the potential of the method.

摘要

在体外放射治疗中,已提出使用调强射野来进行组织和非均匀性补偿,或生成适形剂量分布。多叶准直器可动态用于二维X射线射野的调制。由于计算机和直线加速器技术的进步,高效的动态准直成为可能。与使用补偿器等传统方法相比,它具有许多优势。我们开发了一个程序,该程序根据给定的强度分布计算多叶准直器叶片的运动与监测单位的函数关系,并已将其应用于配备40对多叶准直器的瓦里安直线加速器上。对实验结果的分析证明了该方法的可行性和潜力。

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