Ingal V N, Beliaevskaya E A, Brianskaya A P, Merkurieva R D
X-Ray Laboratory, St Petersburg, Russia.
Phys Med Biol. 1998 Sep;43(9):2555-67. doi: 10.1088/0031-9155/43/9/009.
A new phase radiography technique for investigation and diagnosis of neoplasms in breast tissue is proposed. Forty-four mammography samples with adenocarcinoma that had been prepared after mastectomy were tested in a new phase radiography device. It was shown that the phase images manifest the changes in parenchyma structure due to malignancy and microcalcifications up to 50 microm in size. Results obtained were verified by histological examination. A contrast of the phase images of small microcalcifications and distortions of the stroma architecture ranges up to 40-60%; spatial resolution is about 20 microm. The proposed technique offers outstanding possibilities for digital mammography. The small and large details of structure manifest themselves with practically the same contrast. Phase images differ from those obtained in mammography and many details still require further decoding.
提出了一种用于乳腺组织肿瘤研究与诊断的新型相位射线照相技术。对44个在乳房切除术后制备的腺癌乳腺摄影样本在新型相位射线照相设备中进行了测试。结果表明，相位图像显示了由于恶性肿瘤导致的实质结构变化以及尺寸达50微米的微钙化。所得结果通过组织学检查得到验证。小微钙化的相位图像与基质结构畸变的对比度高达40%-60%；空间分辨率约为20微米。所提出的技术为数字乳腺摄影提供了出色的可能性。结构的小细节和大细节显示出几乎相同的对比度。相位图像与乳腺摄影中获得的图像不同，许多细节仍需要进一步解读。
