Urocanic acid and cutaneous antigen presentation.
作者信息
Lappin M B, Simon J C
机构信息
Department of Dermatology, University of Freiburg, Germany.
出版信息
J Photochem Photobiol B. 1998 Jul 10;44(2):112-6. doi: 10.1016/S1011-1344(98)00129-8.
PMID:9757592
Abstract
Exposure to UVB results in the isomerization of trans-urocanic acid (UCA), localized in the stratum corneum, to cis-UCA. Cis-UCA can mediate at least some of the immunosuppressive effects of UVB, though the mechanism of cis-UCA action remains incompletely defined. Here, we review the evidence that cis-UCA acts through alterations in cutaneous antigen presentation.
摘要
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