Smyth N P
Compr Ther. 1976 Nov;2(11):64-71.
A new J-lead has now been designed and manufactured for both animal and clinical studies. This lead has silastic tines proximal to the electrode, arranged so that they become entangled in the trabeculae of the appendage and hold the lead in place. Studies in ten dogs have shown excellent tissue fixation at the site of the tines, and only minimal scarring occurs at the site of the terminal electrode, with preservation of good P-wave amplitude and good stimulating thresholds for a period of four to five months (Figure 8, see next page). The lead designed for humans has been used successfully in 12 patients. Follow-up now extends to 19 months, with stable P-wave-triggered atrial pacing in eight patients, fixed rate atrial pacing in one, and A-V synchronized pacing in three. No lead dislodgement has occurred.
现已设计并制造出一种新型J形导联,用于动物和临床研究。该导联在电极近端有硅橡胶尖齿,其排列方式使其能缠附于心耳小梁并将导联固定在位。对10只犬的研究表明,尖齿部位的组织固定良好,终端电极部位仅有轻微瘢痕形成,在4至5个月的时间内P波振幅良好且刺激阈值正常(见图8,下一页)。为人类设计的导联已成功应用于12例患者。目前随访已达19个月,8例患者P波触发心房起搏稳定,1例固定频率心房起搏,3例房室同步起搏。未发生导联脱位。