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构巢曲霉的areA(r)突变在仅以铵作为唯一氮源的情况下赋予了低pH敏感性。

The areA(r) mutation of Aspergillus nidulans confers low pH sensitivity in the presence of ammonium as the only nitrogen source.

作者信息

Pereira M, Martinez-Rossi N M

机构信息

Departamento de Genetica, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Brazil.

出版信息

Lett Appl Microbiol. 1998 Jul;27(1):54-6. doi: 10.1046/j.1472-765x.1998.00384.x.

DOI:10.1046/j.1472-765x.1998.00384.x
PMID:9758458
Abstract

The utilization of nitrogen sources by the fungus Aspergillus nidulans is controlled by a mechanism mediated by areA, a wide domain regulatory gene. It has been verified that the strains carrying the mutant allele areAr are inhibited when growing at low pH in the presence of ammonium as the only nitrogen source. The genetic analysis of this marker showed that it apparently maps at the areA locus.

摘要

构巢曲霉对氮源的利用受一个由areA（一个广泛结构域调控基因）介导的机制控制。已经证实，携带突变等位基因areAr的菌株在以铵作为唯一氮源且低pH条件下生长时会受到抑制。对该标记的遗传分析表明，它显然定位于areA基因座。

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