参与氮代谢物阻遏的构巢曲霉nmrA基因的特性分析
Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression.
作者信息
Andrianopoulos A, Kourambas S, Sharp J A, Davis M A, Hynes M J
机构信息
Department of Genetics, University of Melbourne, Parkville, Victoria, Australia.
出版信息
J Bacteriol. 1998 Apr;180(7):1973-7. doi: 10.1128/JB.180.7.1973-1977.1998.
Abstract
The gene nmrA of Aspergillus nidulans has been isolated and found to be a homolog of the Neurospora crassa gene nmr-1, involved in nitrogen metabolite repression. Deletion of nmrA results in partial derepression of activities subject to nitrogen repression similar to phenotypes observed for certain mutations in the positively acting areA gene.
摘要
构巢曲霉的nmrA基因已被分离出来，发现它是粗糙脉孢菌中参与氮代谢物阻遏的nmr - 1基因的同源物。nmrA基因的缺失导致受氮阻遏的活性部分去阻遏，这与在正向作用的areA基因中的某些突变所观察到的表型相似。
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