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[使用激光散射仪评估白内障手术后的炎症反应]

[Evaluation by laser flare meter of the inflammatory response after cataract surgery].

作者信息

Laplace O, Goldschild M, De Saint Jean M, Guepratte N, Baudouin C

机构信息

Service d'Ophtalmologie, Hôpital Ambroise Paré Université Paris V, Boulogne.

出版信息

J Fr Ophtalmol. 1998 Apr;21(4):265-9.

PMID:9759415
Abstract

PURPOSE

To prospectively evaluate use of the laser flare meter the inflammatory response after phacoemulsification with four different types of intraocular lenses.

METHODS

Measurements with the Kowa laser flare meter FC-500 were done before surgery and at 1, 6 and 21 days following standard phacoemulsification with corneal incision in 157 patients. The patients were randomized in four groups to receive HSM IOL (group I), foldable acrylic IOL (group II), foldable three-piece silicone (group III), and foldable single-piece silicone (group IV).

RESULTS

Overall, mean flare values were increased at D1, and decreased rapidly to normal values at D21. Intragroup analysis showed a slight increase of flare value observed in the PMMA group (p = 0.0015) and silicone monobloc group (p = 0.001) at D21 compared to D0. There was no statistical difference found between D0 and D21 in the acrylic and the silicone three pieces groups. At D1, a significant increase of flare values was observed in the PMMA (28.9 ph/ms) and silicone three pieces (28.8 ph/ms) groups, as compared to silicone monobloc group (22 ph/ms). At D21, the acrylic group had a significantly lower mean value than PMMA and silicone monobloc groups. No statistical difference was observed between acrylic and three-piece silicone at D21.

CONCLUSION

This study shows that the inflammation in the four groups was very low after phacoemulsification by a corneal incision and attempts to explain the impact of the incision length on the breakdown of blood-aqueous barrier.

摘要

目的

前瞻性评估使用激光散射仪测量四种不同类型人工晶状体在白内障超声乳化术后的炎症反应。

方法

对157例患者在标准角膜切口白内障超声乳化术前及术后1天、6天和21天使用Kowa激光散射仪FC - 500进行测量。患者被随机分为四组,分别植入HSM人工晶状体(I组)、可折叠丙烯酸酯人工晶状体(II组)、可折叠三片式硅胶人工晶状体(III组)和可折叠单片式硅胶人工晶状体(IV组)。

结果

总体而言,平均散射值在术后第1天升高,并在第21天迅速降至正常水平。组内分析显示,与术前相比,聚甲基丙烯酸甲酯(PMMA)组(p = 0.0015)和单片式硅胶组(p = 0.001)在术后第21天散射值略有升高。丙烯酸酯组和三片式硅胶组在术前和术后第21天之间未发现统计学差异。术后第1天,PMMA组(28.9 ph/ms)和三片式硅胶组(28.8 ph/ms)的散射值显著高于单片式硅胶组(22 ph/ms)。术后第21天,丙烯酸酯组的平均值显著低于PMMA组和单片式硅胶组。术后第21天,丙烯酸酯组和三片式硅胶组之间未观察到统计学差异。

结论

本研究表明,角膜切口白内障超声乳化术后四组的炎症反应均很低,并试图解释切口长度对血 - 房水屏障破坏的影响。

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