LiPuma J J
Department of Pediatrics, Allegheny University of the Health Sciences, Philadelphia, Pennsylvania, USA.
Clin Chest Med. 1998 Sep;19(3):473-86, vi. doi: 10.1016/s0272-5231(05)70094-0.
Although Burkholderia cepacia colonizes a relatively small proportion of individuals with cystic fibrosis (CF), it is associated with significant morbidity and mortality, and has had a profound impact on infection control practices. This article reviews the current understanding of the epidemiology of B. cepacia infection, describes important recent developments in the microbiology and taxonomy of this species, and presents issues that remain obstacles to defining the optimal management of B. cepacia infection in CF.
尽管洋葱伯克霍尔德菌仅定植于相对一小部分囊性纤维化（CF）患者体内，但它与显著的发病率和死亡率相关，并且对感染控制措施产生了深远影响。本文综述了目前对洋葱伯克霍尔德菌感染流行病学的认识，描述了该菌种在微生物学和分类学方面的重要最新进展，并提出了在确定CF患者洋葱伯克霍尔德菌感染的最佳管理方案时仍然存在障碍的问题。
