Reznikoff-Etievant M F, Richter N, Sylvestre R, Hors J, Intrator L, Laurent J, Lagrue G
Pathol Biol (Paris). 1978 Feb;26(2):103-6.
The study deals with a family of 22 members spreading over four generations; 14 members suffer from hereditary angio-neurotic edema; all of them have been typed for 30 antigens of the A and B loci in the HLA System and for ABO and Rhesus erythrocyte markers. There is no connection between the disease and any of the markers considered. As for the HLA system, there should be at least 7 chromosomic recombinants to account for the relationship with one of the haplotypes involved.
该研究涉及一个四代同堂的22口之家；其中14人患有遗传性血管神经性水肿；所有成员都已针对HLA系统中A和B位点的30种抗原以及ABO和恒河猴红细胞标记物进行了分型。该疾病与所考虑的任何一种标记物之间均无关联。至于HLA系统，至少应有7个染色体重组体才能解释与其中一种相关单倍型的关系。
