Blekher T, Christian J C, Abel L A, Yee R D
Department of Ophthalmology, Indiana University School of Medicine, Indianapolis 46202-5175, USA.
Invest Ophthalmol Vis Sci. 1998 Oct;39(11):2186-90.
The influence of genetic and prenatal environmental factors on characteristics of saccadic performance were evaluated in young monozygotic (MZ) twins (8-19 years old) of known chorion type.
Saccadic eye movements were recorded using an infrared system. Saccadic latency, accuracy, and parameters of amplitude-peak velocity exponential equation (main sequence) were quantified.
Intraclass correlations of saccadic parameters differed significantly from zero for monochorionic and dichorionic MZ twins. The within-pair mean squares were significantly less, and intraclass correlations were significantly higher in monochorionic than in dichorionic twins for latency and were similar for other saccadic parameters (accuracy, slope of main sequence, and peak velocity for 15 degrees saccades).
These findings confirmed previous reports that saccadic parameters of MZ twins are significantly correlated and indicated that similarity of these parameters seen in MZ twins may be driven both by genetic and by prenatal environmental factors.
在已知绒毛膜类型的年轻同卵（MZ）双胞胎（8至19岁）中，评估遗传和产前环境因素对扫视运动特征的影响。
使用红外系统记录眼球扫视运动。对扫视潜伏期、准确性以及幅度-峰值速度指数方程（主序列）的参数进行量化。
单绒毛膜和双绒毛膜MZ双胞胎的扫视参数组内相关性显著不同于零。单绒毛膜双胞胎的组内均方显著更小，且在潜伏期方面，单绒毛膜双胞胎的组内相关性显著高于双绒毛膜双胞胎，而其他扫视参数（准确性、主序列斜率以及15度扫视的峰值速度）的组内相关性相似。
这些发现证实了先前的报道，即MZ双胞胎的扫视参数显著相关，并表明在MZ双胞胎中观察到的这些参数的相似性可能由遗传因素和产前环境因素共同驱动。
