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绒毛膜类型对单卵双胞胎正常和异常发育变异的影响。

The effects of chorion type on normal and abnormal developmental variation in monozygous twins.

作者信息

Melnick M, Myrianthopoulos N C

出版信息

Am J Med Genet. 1979;4(2):147-56. doi: 10.1002/ajmg.1320040207.

DOI:10.1002/ajmg.1320040207
PMID:517573
Abstract

To determine the effects, if any, of chorion type on normal and abnormal developmental variation in monozygous (MZ) twins, we tested the hypothesis that disparate environments that are related to chorion type have no effect on this variation. The parameters studied included congenital anomalies and dermatoglyphics (total ridge count and right-left asymmetry). With the exception of total ridge count, analyses of these data failed to reject the null hypothesis. Dichorionic MZ twins had a significantly greater within-pair variation than monochorionic MZ twins for total ridge count. In summary, then, these data could offer little support to prior speculation that monochorial placenta may present less favorable environments for feta development.

摘要

为了确定绒毛膜类型对单卵(MZ)双胞胎正常和异常发育变异的影响(如果有),我们检验了以下假设:与绒毛膜类型相关的不同环境对这种变异没有影响。所研究的参数包括先天性异常和皮纹学(总嵴数和左右不对称性)。除总嵴数外,对这些数据的分析未能拒绝零假设。在总嵴数方面,双绒毛膜MZ双胞胎的同对内变异显著大于单绒毛膜MZ双胞胎。总之,这些数据几乎无法支持先前的推测,即单绒毛膜胎盘可能为胎儿发育提供不太有利的环境。

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The effects of chorion type on normal and abnormal developmental variation in monozygous twins.绒毛膜类型对单卵双胞胎正常和异常发育变异的影响。
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引用本文的文献

1
The Prenatal Environment in Twin Studies: A Review on Chorionicity.双胎研究中的产前环境:关于绒毛膜性的综述
Behav Genet. 2016 May;46(3):286-303. doi: 10.1007/s10519-016-9782-6. Epub 2016 Mar 5.
2
Twinning and neural tube defects: environmental factors.双胎妊娠与神经管缺陷:环境因素
Am J Hum Genet. 1995 Jul;57(1):193-4; author reply 195.
3
Epidemiology of major congenital heart defects in Sweden, 1981-1986.1981 - 1986年瑞典主要先天性心脏缺陷的流行病学
J Epidemiol Community Health. 1992 Jun;46(3):211-5. doi: 10.1136/jech.46.3.211.