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手术切断家兔内侧基底下丘脑对交配后反射性排卵的影响。

Effect of surgical disconnection of the medial basal hypothalamus on postcoital reflex ovulation in the rabbit.

作者信息

Voloschin L M, Gallardo E A

出版信息

Endocrinology. 1976 Oct;99(4):959-62. doi: 10.1210/endo-99-4-959.

DOI:10.1210/endo-99-4-959
PMID:976196
Abstract

The effects of hypothalamic transections of varying lengths on reflex ovulation in the rabbit are reported. Circular cuts which surgically isolated the medial basal hypothalamus (MBH) from the remainder of the brain did not prevent copulation 4 to 24 h later, but did block reflex ovulation. On the contrary, hemicircular cuts of either the rostral, caudal or one lateral haf of the circular cut did not prevent reflex ovulation. These results suggest that coital stimuli reach the MBH through a diffuse network of fibers and that only very extensive deaferrentation of the MBH can cause blockade of ovulation in rabbits. These data are compared with results of other investigators in which anterior deafferentation of the MBH blocked reflex and spontaneous ovulation in rats.

摘要

本文报道了不同长度的下丘脑横断对家兔反射性排卵的影响。通过手术将内侧基底下丘脑(MBH)与脑的其余部分分离的环形切口,并不妨碍4至24小时后的交配,但确实会阻断反射性排卵。相反,环形切口的头侧、尾侧或一侧半的半圆形切口并不妨碍反射性排卵。这些结果表明,交配刺激通过一个弥散的纤维网络到达MBH,并且只有非常广泛的MBH传入阻滞才能导致家兔排卵的阻断。这些数据与其他研究者的结果进行了比较,在其他研究中,MBH的前部传入阻滞阻断了大鼠的反射性和自发性排卵。

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