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[结肠原发性静脉曲张。胃肠道出血的罕见原因]

[Primary varices of the colon. A rare cause of gastrointestinal bleeding].

作者信息

Schmidt C, Klomp H J, Doniec M, Grimm H

机构信息

Klinik für Allgemeine und Thoraxchirurgie, Christian-Albrechts-Universität zu Kiel.

出版信息

Dtsch Med Wochenschr. 1998 Sep 11;123(37):1069-72. doi: 10.1055/s-2007-1024127.

Abstract

HISTORY

A 34-year-old patient presented with a two-day history of passing bright-red blood with his stools. There was no contributory past or family history and he had no accompanying symptoms.

INVESTIGATIONS

Colonoscopy revealed many varices in the colon and terminal ileum without an active source of bleeding. Angiography failed to demonstrate any bleeding or vascular anomaly in the splanchnic region. Abdominal ultrasound and gastroscopy as well as biochemical tests did not indicate portal hypertension or liver cirrhosis.

TREATMENT AND COURSE

On the night of admission there was a renewed fall in haemoglobin concentration. Emergency colonoscopy again failed to discover a source of bleeding. After transfusion of four units of erythrocyte concentrate the further course was uneventful. 8 months and 3 years later there were further episodes of marked bleeding per rectum. At the latest admission no source for the bleeding was found but there was some blood oozing in the sigmoid colon. Biochemical tests were unremarkable. The large varices were again seen in the colon and terminal ileum. Gastroscopy, Doppler sonography of the liver and repeat abdominal sonography again failed to demonstrate portal vein thrombosis, liver cirrhosis or portal hypertension.

CONCLUSION

In case of colonic varices the differential diagnosis should include portal hypertension with chronic liver disease, portal vein thrombosis, vascular anomalies or postoperative complications. The treatment of primary varices, which are rare, is conservative.

摘要

病史

一名34岁患者,有两天排鲜红色血便的病史。既往史和家族史均无相关情况,且无伴随症状。

检查

结肠镜检查发现结肠和回肠末端有许多静脉曲张,无活动性出血源。血管造影未显示内脏区域有任何出血或血管异常。腹部超声、胃镜检查及生化检查均未提示门静脉高压或肝硬化。

治疗及病程

入院当晚血红蛋白浓度再次下降。急诊结肠镜检查再次未发现出血源。输注4单位红细胞浓缩液后,病情平稳。8个月和3年后又出现多次明显的直肠出血。最近一次入院时未发现出血源,但乙状结肠有渗血。生化检查无异常。结肠和回肠末端再次发现大的静脉曲张。胃镜检查、肝脏多普勒超声检查及重复腹部超声检查均未显示门静脉血栓形成、肝硬化或门静脉高压。

结论

对于结肠静脉曲张,鉴别诊断应包括伴有慢性肝病的门静脉高压、门静脉血栓形成、血管异常或术后并发症。原发性静脉曲张较为罕见,治疗以保守为主。

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