Krylov I N
Laboratory for the Physiology of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia.
Neurosci Behav Physiol. 1998 Jul-Aug;28(4):402-8. doi: 10.1007/BF02464795.
Studies were made of psychomotor responses and accompanying cortical evoked potentials in healthy subjects and patients with Parkinson's disease. Measurements showed that delays in a variety of psychomotor responses resulted from delays in movement initiation. The frontal regions showed increases in the N2 component of evoked potentials and delayed development of P3 waves. It is suggested that delayed initiation of movements in patients with Parkinson's disease might be associated with strengthening of frontal inhibitory systems, preventing the onset of movements.
对健康受试者和帕金森病患者的精神运动反应及伴随的皮层诱发电位进行了研究。测量结果表明，各种精神运动反应的延迟是由运动启动延迟导致的。额叶区域诱发电位的N2成分增加，P3波发育延迟。有人认为，帕金森病患者运动启动延迟可能与额叶抑制系统增强有关，从而阻止了运动的发生。
