[人类正常精神运动反应及基底神经节功能障碍期间内源性诱发电位的特征]
[The characteristics of endogenous evoked potentials during normal psychomotor reactions and during basal ganglionic dysfunction in man].
作者信息
Krylov I N
出版信息
Fiziol Zh Im I M Sechenova. 1995 Apr;81(4):51-62.
PMID:7581576
Abstract
Averaged cortical EPs (or the ERPs) in response to light stimuli were analysed in the Fz, Pz and Oz leads in healthy subjects and in Parkinsonian patients. The largest CNV and Nd (negative difference) were recorded in the Fz, the negative waves being inversely related to each other. A delay in psychomotor responses was accompanied by a decrease in the endogenous ERPs in all the leads in Parkinsonian patients. The ERp attenuation seems to be connected with the cortical hypoactivation due to the basal ganglia disfunction.
摘要
在健康受试者和帕金森病患者中，分析了Fz、Pz和Oz导联对光刺激的平均皮层诱发电位（或事件相关电位）。在Fz导联记录到最大的关联性负变（CNV）和负向差值（Nd），负向波彼此呈负相关。帕金森病患者所有导联的内源性事件相关电位降低，同时伴有精神运动反应延迟。事件相关电位衰减似乎与基底神经节功能障碍导致的皮层激活不足有关。
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