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西班牙巴塞罗那白内障手术的有效性:一项国际研究的现场结果。巴塞罗那I-PORT研究人员。国际患者结局研究团队。

Effectiveness of cataract surgery in Barcelona, Spain site results of an international study. Barcelona I-PORT investigators. International Patient Outcomes Research Team.

作者信息

Espallargues M, Alonso J

机构信息

Health Services Research Unit, Institut Municipal d'Investigació Mèdica, Barcelona, Spain.

出版信息

J Clin Epidemiol. 1998 Oct;51(10):843-52. doi: 10.1016/s0895-4356(98)00067-5.

Abstract

OBJECTIVES

To describe the impact of cataract surgery on visual function and health status in terms of clinical indicators as well as perceived health and functional capacity, and to identify patient characteristics and differences in clinical management that might affect outcomes.

SUBJECTS AND METHODS

Observational longitudinal study of a cohort of 218 patients aged 50 or older undergoing first eye cataract surgery. Patients were evaluated pre- and postoperatively by clinical examinations (visual acuity [VA], ocular and medical comorbidity) and standardized telephone interviews. Main outcome measures included: the VF-14 Visual Function Index, the Cataract Symptom Score (CSS), the Sickness Impact Profile (SIP), and global measures of patients' trouble and satisfaction with vision.

RESULTS

Significant improvement in all outcomes measures were observed at 4 months postoperatively (P < 0.001). However, the proportion of improved patients varied according to the outcome considered: VA (87%), CSS (72%), VF-14 (62%), and SIP (38%). Patient characteristics associated with higher a level of improvement were: worse preoperative visual function (VA, CSS, VF-14) (P < 0.001), less ocular comorbidity (P < 0.05), less postoperative complications (P < 0.05) and better preoperative general health status (SIP) (P < 0.01). The differences in clinical management were not associated with the outcomes (effectiveness) of surgery.

CONCLUSIONS

A large proportion of patients benefit from cataract surgery, the greatest gain corresponding to visual function rather than to general health status. Since effectiveness of surgery is unrelated to operative procedures, less costly practices (i.e., day case surgery and loco-regional anesthesia) should be promoted.

摘要

目的

从临床指标以及感知到的健康和功能能力方面描述白内障手术对视觉功能和健康状况的影响,并确定可能影响手术结果的患者特征及临床管理差异。

对象与方法

对218例年龄在50岁及以上接受第一眼白内障手术的患者进行队列观察性纵向研究。术前和术后通过临床检查(视力[VA]、眼部和内科合并症)及标准化电话访谈对患者进行评估。主要结局指标包括:VF - 14视觉功能指数、白内障症状评分(CSS)、疾病影响量表(SIP)以及患者视力问题和满意度的总体指标。

结果

术后4个月时,所有结局指标均有显著改善(P < 0.001)。然而,改善患者的比例因所考虑的结局指标而异:视力(87%)、CSS(72%)、VF - 14(62%)和SIP(38%)。与改善程度较高相关的患者特征为:术前视觉功能较差(VA、CSS、VF - 14)(P < 0.001)、眼部合并症较少(P < 0.05)、术后并发症较少(P < 0.05)以及术前总体健康状况较好(SIP)(P < 0.01)。临床管理差异与手术结局(有效性)无关。

结论

大部分患者从白内障手术中获益,最大获益在于视觉功能而非总体健康状况。由于手术有效性与手术操作无关,应推广成本较低的做法(即日间手术和局部区域麻醉)。

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