Roorda R J, Walhof C M, Brand P L
Ziekenhuis De Weezenlanden en St. Sophia Ziekenhuis, afd. Kinderlongziekten, Zwolle.
Ned Tijdschr Geneeskd. 1998 Jul 18;142(29):1658-62.
Traditionally, steaming with warm moist air was recommended for the treatment of subglottic laryngitis (pseudocroup). However, no favourable effect has ever been demonstrated. Consequently, steaming is no longer to be advised. Systemic corticosteroids, already of proven effectiveness in severe croup, were shown to be also effective when administered in a single oral dose in moderately severe disease. Besides, in various studies, nebulisation of budesonide (2000 micrograms) with a jet nebuliser had a good effect on the clinical course of croup. However, dose-effect studies are still lacking. A single dose of corticosteroids, either systemic or inhaled via a jet nebuliser, should be the first line therapy in moderate and severe croup syndrome. In milder cases no specific treatment is needed as the disease is self-limiting.
传统上，建议用温热潮湿的空气进行蒸汽吸入治疗声门下喉炎（假膜性喉炎）。然而，从未证明其有良好效果。因此，不再建议进行蒸汽吸入治疗。全身用皮质类固醇在重症喉炎中已被证明有效，在中度重症疾病中单次口服给药也显示出有效。此外，在各项研究中，用喷射雾化器雾化布地奈德（2000微克）对喉炎的临床病程有良好效果。然而，仍缺乏剂量效应研究。单次剂量的皮质类固醇，无论是全身用药还是通过喷射雾化器吸入，都应作为中度和重度喉炎综合征的一线治疗方法。在较轻的病例中，由于该病具有自限性，无需特殊治疗。
