Dreassi E, Bonifacio M, Corti P
Department of Pharmaceutical and Chemical Technology, University of Siena, Italy.
Food Addit Contam. 1998 May-Jun;15(4):466-72. doi: 10.1080/02652039809374667.
Irganox 1330 (1,3,5-trimethyl-2,4,5-tris(3',5'-ditert-butyl)-4'-hydroxybenzyl)- benzene) (I), an alkylphenol compound used as antioxdiant in the production of high density polyethylene (HDPE), was the subject of this study. The quantity of I given up by polyethylene samples of different thickness to aqueous and lipophilic media simulating food was studied by planar chromatography (PC). The manner of antioxidant release was also investigated. The chromatographic method developed was found satisfactory for the quantification of I in the migration studies undertaken, and had quantification limits (12 ng/deposit) suitable for quality control of HDPE.
抗氧剂1330（1,3,5-三甲基-2,4,5-三（3',5'-二叔丁基）-4'-羟基苄基）苯（I）是一种在高密度聚乙烯（HDPE）生产中用作抗氧化剂的烷基酚化合物，是本研究的对象。通过平面色谱法（PC）研究了不同厚度的聚乙烯样品向模拟食品的水性和亲脂性介质中释放I的量。还研究了抗氧化剂的释放方式。所开发的色谱方法在进行的迁移研究中对I的定量测定令人满意，并且具有适用于HDPE质量控制的定量限（12 ng/沉积物）。
