遗传性糖尿病前期小鼠的肾脏葡萄糖基转移酶活性升高。
Elevated kidney glucosyltransferase activity in genetic prediabetic mice.
作者信息
Reddi A S, Oppermann W, Reddy M P, Velasco C A, Camerini-Davalos R A
出版信息
Experientia. 1976 Oct 15;32(10):1237-8. doi: 10.1007/BF01953068.
PMID:976428
Abstract
Glucosyltransferase activity in the renal cortex of genetic diabetic KK mice was significantly increased at 40 days of age when compared to that of Swiss albino and F1 hybrid mice. This increase in enzyme activity in the absence of glucose intolerance can be regarded as an earlier genetic marker for the diagnosis of diabetic microangiopathy.
摘要
与瑞士白化小鼠和F1杂种小鼠相比，遗传性糖尿病KK小鼠肾皮质中的葡萄糖基转移酶活性在40日龄时显著增加。在无葡萄糖不耐受情况下酶活性的这种增加可被视为诊断糖尿病微血管病变的一种早期遗传标志物。
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