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保幼激素类似物可抵消蜕皮激素对克隆果蝇细胞系生长的刺激和抑制作用。

Juvenile hormone analogue counteracts growth stimulation and inhibition by ecdysones in clonal Drosophila cell line.

作者信息

Wyss C

出版信息

Experientia. 1976 Oct 15;32(10):1272-4. doi: 10.1007/BF01953088.

DOI:10.1007/BF01953088
PMID:976438
Abstract

Depending on concentration, ecdysones either stimulate or inhibit proliferation of a clonal Drosophila cell line. Both effects are counteracted by ethyl dichlorofarnesoate, a juvenile hormone analogue, which by itself is growth inhibitory. Qualitatively no difference was seen between alpha- and beta-ecdysone.

摘要

根据浓度不同，蜕皮激素既可以刺激也可以抑制克隆的果蝇细胞系的增殖。这两种作用都可被二氯法尼酯（一种保幼激素类似物）抵消，而二氯法尼酯本身具有生长抑制作用。在α-蜕皮激素和β-蜕皮激素之间未观察到定性差异。

相似文献

1
Juvenile hormone analogue counteracts growth stimulation and inhibition by ecdysones in clonal Drosophila cell line.保幼激素类似物可抵消蜕皮激素对克隆果蝇细胞系生长的刺激和抑制作用。
Experientia. 1976 Oct 15;32(10):1272-4. doi: 10.1007/BF01953088.
2
The assay of ecdysones and juvenile hormones on Drosophila imaginal disks in vitro.果蝇成虫盘体外蜕皮激素和保幼激素的测定
J Insect Physiol. 1972 Jun;18(6):1115-23. doi: 10.1016/0022-1910(72)90146-1.
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Effects of juvenile hormone on the ecdysone response of Drosophila Kc cells.保幼激素对果蝇Kc细胞蜕皮激素反应的影响。
Dev Genet. 1989;10(3):177-88. doi: 10.1002/dvg.1020100307.
4
Ecdysone-induced changes in morphology and protein synthesis in Drosophila cell cultures.蜕皮激素诱导果蝇细胞培养物中形态和蛋白质合成的变化。
Dev Biol. 1978 Feb;62(2):498-511. doi: 10.1016/0012-1606(78)90231-2.
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Effects and interactions of juvenile hormone and beta-ecdysone on Drosophila imaginal discs cultured in vitro.保幼激素和β-蜕皮激素对体外培养的果蝇成虫盘的作用及相互作用
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Effects of ecdysone and juvenile hormone on DNA metabolism of imaginal disks of Drosophila melanogaster.蜕皮激素和保幼激素对黑腹果蝇成虫盘DNA代谢的影响。
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J Insect Physiol. 1976;22(12):1697-707. doi: 10.1016/0022-1910(76)90063-9.
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Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster. VI. Inhibition by juvenile hormones.果蝇多线染色体中蜕皮激素诱导的顺序基因激活。VI. 保幼激素的抑制作用。
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Effects of ecdysone and juvenile hormone on epidermal cell development in Hyalophora cecropia.
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引用本文的文献

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Rouxs Arch Dev Biol. 1992 Dec;202(1):23-35. doi: 10.1007/BF00364594.
2
The morphological response of Kc-H cells to ecdysteroids: Hormonal specificity.Kc-H细胞对蜕皮甾体的形态学反应：激素特异性。
Wilehm Roux Arch Dev Biol. 1980 Feb;189(1):1-15. doi: 10.1007/BF00848562.
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本文引用的文献

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Hormonal conditions necessary for evolution of the ovary in the pupa of Tenebrio molitor (Coleoptera).黄粉虫（鞘翅目）蛹期卵巢发育所需的激素条件。
Gen Comp Endocrinol. 1971 Dec;17(3):467-78. doi: 10.1016/0016-6480(71)90181-x.
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Metabolic and hormonal studies on two insect cell lines.对两种昆虫细胞系的代谢和激素研究。
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In vitro culture of Drosophila melanogaster embryonic cells.黑腹果蝇胚胎细胞的体外培养。
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cDNA clones for the ecdysone-inducible polypeptide (EIP) mRNAs of Drosophila Kc cells.果蝇 Kc 细胞蜕皮激素诱导多肽（EIP）mRNA 的 cDNA 克隆。
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The apparent requirement of two hormones, alpha- and beta-ecdysone, for molting induction in insects.昆虫蜕皮诱导显然需要两种激素，即α-蜕皮激素和β-蜕皮激素。
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Deposition of insect cuticle in vitro: differential responses to alpha- and beta-ecdysone.昆虫表皮体外沉积：对α-蜕皮激素和β-蜕皮激素的不同反应
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Action of insect hormones at the cellular level. Morphological changes of a diploid cell line of Drosophila melanogaster, treated with ecdysone and several analogues in vitro.昆虫激素在细胞水平上的作用。体外经蜕皮激素及几种类似物处理的黑腹果蝇二倍体细胞系的形态变化。
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7
Effects of - and -ecdysone on in vitro diploid cell multiplication in Drosophila melanogaster.α-蜕皮激素和β-蜕皮激素对黑腹果蝇体外二倍体细胞增殖的影响。
Nat New Biol. 1972 Aug 23;238(86):250-1. doi: 10.1038/newbio238250a0.
8
Relative activities of alpha-ecdysone and beta-ecdysone for the differentiation in vitro of Drosophila melanogaster imaginal discs.α-蜕皮激素和β-蜕皮激素对黑腹果蝇成虫盘体外分化的相对活性。
Cell. 1974 Oct;3(2):141-3. doi: 10.1016/0092-8674(74)90118-4.
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Ecdysone levels during metamorphosis of Drosophila melanogaster.黑腹果蝇变态过程中的蜕皮激素水平。
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Juvenile hormone and the adult development of Drosophila.保幼激素与果蝇的成虫发育
Biol Bull. 1974 Aug;147(1):119-35. doi: 10.2307/1540573.