Duffy K R, Murphy K M, Jones D G
Department of Psychology, McMaster University, Hamilton, Ontario, Canada.
Vis Neurosci. 1998 Sep-Oct;15(5):831-9. doi: 10.1017/s0952523898155049.
Development and growth of V1 begins during embryogenesis and continues postnatally. The growth of V1 has direct implications on the organization of features such as the retinotopic map and the pattern of visual cortical columns. We have examined the postnatal growth and two-dimensional shape of V1 in macaque monkeys, cats, and rats. The perimeter, area, and anterior-posterior length of V1 were measured from unfolded and flattened sections from neonatal and adult animals from each of these species. Although there were substantial differences in the overall amount of postnatal growth, from 18% in macaque monkeys to more than 100% in cats, in all three species the shape of V1 did not change during development. Thus, growth of the mammalian visual cortex is well described as an isotropic expansion, so the layout of the global features, such as the arrangement of ocular dominance columns and the retinotopic map, does not need to change during development. Furthermore, quantification of the shape confirms the observations that there is a similar, egg-like oval shape to the visual cortex of these mammalian species.
初级视皮层（V1）的发育和生长始于胚胎期，并在出生后持续进行。V1的生长对视皮层特征组织，如视网膜拓扑图和视皮层柱模式，有着直接影响。我们研究了猕猴、猫和大鼠出生后V1的生长情况及二维形状。通过对这些物种新生和成年动物展开并平整后的切片进行测量，得出了V1的周长、面积和前后长度。尽管出生后生长的总量存在显著差异，从猕猴的18%到猫的超过100%，但在所有这三个物种中，V1的形状在发育过程中并未改变。因此，哺乳动物视皮层的生长可以很好地描述为各向同性扩张，所以诸如眼优势柱排列和视网膜拓扑图等全局特征的布局在发育过程中无需改变。此外，形状的量化证实了这些哺乳动物物种的视皮层具有类似蛋形的椭圆形这一观察结果。
