DiFronzo L A, Egrari S, O'Connell T X
Department of Surgery, Kaiser Permanente Medical Center, Los Angeles, California, USA.
Am Surg. 1998 Oct;64(10):917-20.
Biliary-enteric anastomosis has long been associated with significant complications of early bile leak, cholangitis, and late stricture formation, and controversy exists regarding which operative technique best prevents these problems. Biliary-enteric anastomosis was performed using a single-layer running 4-0 polyglactin (Vicryl) suture, without a transanastomotic stent, in 97 patients by a single surgeon over a 17-year period. Indications for operation included malignant obstruction (84.5%), benign stricture, choledocholithiasis, and choledochal cyst. The most common operation performed was a choledochoduodenostomy; the remaining operations were either Roux-en-Y choledochojejunostomy, hepaticoduodenostomy, or Roux-en-Y hepaticojejunostomy. Complications occurred in 14.1 per cent of patients; there was one perioperative death. There was only one case of anastomotic leak (1%), which resolved spontaneously within 1 week. Mean hospital stay was 8.7 days. The mean follow-up was 13.1 months in all patients. Among patients with benign disorders of the biliary tract, the mean follow-up was 21 months, during which time no patient developed an anastomotic stricture. One patient experienced postoperative cholangitis, although not as a result of anastomotic stricture. Biliary-enteric anastomosis for both benign and malignant disorders can be safely performed using a running, absorbable suture without a stent.
长期以来,胆肠吻合术一直与早期胆漏、胆管炎和晚期狭窄形成等严重并发症相关,关于哪种手术技术能最好地预防这些问题存在争议。在17年的时间里,由一位外科医生使用4-0聚乙醇酸(薇乔)单股连续缝线进行胆肠吻合术,不放置经吻合口支架,共97例患者。手术适应证包括恶性梗阻(84.5%)、良性狭窄、胆总管结石和胆总管囊肿。最常施行的手术是胆总管十二指肠吻合术;其余手术为 Roux-en-Y 胆总管空肠吻合术、肝十二指肠吻合术或 Roux-en-Y 肝空肠吻合术。14.1%的患者发生了并发症;有1例围手术期死亡。仅1例发生吻合口漏(1%),在1周内自行愈合。平均住院时间为8.7天。所有患者的平均随访时间为13.1个月。在患有良性胆道疾病的患者中,平均随访时间为21个月,在此期间无患者发生吻合口狭窄。1例患者发生术后胆管炎,但并非由吻合口狭窄所致。对于良性和恶性疾病,使用连续可吸收缝线且不放置支架进行胆肠吻合术是安全可行的。