来自人5型腺病毒的E1B 55千道尔顿蛋白的RNA结合活性
RNA-binding activity of the E1B 55-kilodalton protein from human adenovirus type 5.
作者信息
Horridge J J, Leppard K N
机构信息
Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
出版信息
J Virol. 1998 Nov;72(11):9374-9. doi: 10.1128/JVI.72.11.9374-9379.1998.
Abstract
The human adenovirus 5 E1B 55-kDa protein is required for efficient nucleocytoplasmic transport of late viral mRNAs. This protein is shown to have RNA-binding activity which maps to a region of the protein with homology to a family of RNA-binding proteins and which has been shown previously to be essential for functionality of the protein in vivo.
摘要
人腺病毒5型E1B 55 kDa蛋白是晚期病毒mRNA高效核质转运所必需的。该蛋白具有RNA结合活性，其定位到与RNA结合蛋白家族具有同源性的蛋白区域，并且先前已证明该区域对于该蛋白在体内的功能至关重要。
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