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[鼻腔双侧封闭。一种治疗遗传性出血性毛细血管扩张症严重复发性鼻出血的原创手术技术]

[Bilateral closure of the nasal cavity. An original surgical technique of treatment of severe recurrent epistaxis in Rendu-Osler disease].

作者信息

Serrano E, Percodani J, Pessey J J

机构信息

Service d'ORL, CHU de Rangueil, Toulouse.

出版信息

Ann Otolaryngol Chir Cervicofac. 1998 Jun;115(3):169-73.

PMID:9765720
Abstract

In the Rendu Osler disease, epistaxis are seen in 80 to 90% of patients, and the multiple treatments that have been proposed have each shown their failure to achieve satisfactory results. We propose, in the case of abundant epistaxis, a bilateral closure of the nasal cavity. This technique has been initially described by Young in 1967 in the treatment of chronic atrophic rhinitis. This operation was carried out in two patients who presented with serious daily epistaxis, poorly tolerated, and refractory to several treatments. Neither of these patients has presented a post-operative bleeding episode with a one year and six months follow-up respectively. Anatomically, the results are satisfactory in both patients, with total closure of the nasal cavity. Functionally, both patients are satisfied, with an appreciable improvement in the quality of life despite total nasal obstruction.

摘要

在遗传性出血性毛细血管扩张症中,80%至90%的患者会出现鼻出血,而此前提出的多种治疗方法均未能取得满意效果。对于鼻出血量大的情况,我们建议进行双侧鼻腔封闭术。该技术最初由扬于1967年描述用于治疗慢性萎缩性鼻炎。对两名每日鼻出血严重、耐受性差且对多种治疗均无效的患者实施了此手术。在分别为期一年零六个月的随访中,这两名患者均未出现术后出血情况。从解剖学角度看,两名患者的鼻腔均完全封闭,结果令人满意。从功能角度看,两名患者均表示满意,尽管鼻腔完全堵塞,但生活质量有明显改善。

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