Moura A M, Simpkins H
Mol Cell Endocrinol. 1976 Oct;5(5):349-57. doi: 10.1016/0303-7207(76)90017-4.
Determinations of the calcium pools in myocardial cells in vitro have shown the existence of at least three pools of exchangeable calcium. Epinephrine and glucagon were found to produce significant increases in the size of the two slower exchanging pools. Prostaglandins E1 and F1alpha also increased significantly calcium pool size whereas E2 and F2alpha did not; results which correlate well with the effects of the two former prostaglandins on intracellular cAMP levels. The results imply that these agents cause small, but significant, changes in the transmembrane exchange of calcium and large increases in the intracellular calcium pool. Effects which may involve the direct or indirect action of cAMP.
体外对心肌细胞中钙池的测定表明，至少存在三个可交换钙池。已发现肾上腺素和胰高血糖素会使两个交换较慢的钙池大小显著增加。前列腺素E1和F1α也显著增加了钙池大小，而E2和F2α则没有；这些结果与前两种前列腺素对细胞内cAMP水平的影响密切相关。结果表明，这些物质会引起钙跨膜交换的微小但显著的变化，并使细胞内钙池大幅增加。这些作用可能涉及cAMP的直接或间接作用。
