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孕中期紧急宫颈环扎术:一项为期十年的单机构回顾性研究。

Mid-trimester emergent cerclage: a ten year single institution review.

作者信息

Chasen S T, Silverman N S

机构信息

Department of Obstetrics and Gynecology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.

出版信息

J Perinatol. 1998 Sep-Oct;18(5):338-42.

PMID:9766407
Abstract

OBJECTIVE

To evaluate clinical factors associated with both time gained in utero and gestational age at delivery in patients undergoing placement of emergent cerclages.

STUDY DESIGN

Retrospective chart review of 75 patients who underwent nonprophylactic cerclages from 1984 to 1994 at Thomas Jefferson University Hospital was performed. Clinical variables evaluated included gestational age at cerclage, gestational age at delivery, cervical dilation at presentation, and presence or absence of bulging membranes on admission. Presence or absence of clinical symptoms at presentation or historic risk factors for incompetent cervix were also noted. Noncontinuous data were analyzed using chi2 or Fisher's exact test; continuous data were compared with either Student's t or Mann-Whitney U tests.

RESULTS

The mean gestational age at time of cerclage placement was 19.1 +/- 3.8 weeks, with a median of 12 weeks gained in utero. Overall, 65% of patients delivered at > or =28 weeks, with 49% delivering at > or =34 weeks. Patients with bulging membranes were more likely to be >2 cm dilated (58% vs. 0%; p < 0.001) and to present at > or =20 weeks gestational age (69% vs. 28%; p < 0.001). They also gained less time after cerclage placement (median 6.4 vs. 17.0 weeks; p < 0.001) and were less likely to reach either 28 weeks (44% vs. 85%; p < 0.001) or 34 weeks (31% vs. 67%; p = 0.004) at delivery.

CONCLUSION

The presence of bulging membranes or advanced dilation at presentation was associated with lower cerclage-to-delivery intervals as well as a lower chance of reaching 28 weeks of gestation.

摘要

目的

评估接受紧急宫颈环扎术患者的宫内孕周增加时间及分娩时孕周相关的临床因素。

研究设计

对1984年至1994年在托马斯·杰斐逊大学医院接受非预防性宫颈环扎术的75例患者进行回顾性病历审查。评估的临床变量包括环扎时孕周、分娩时孕周、就诊时宫颈扩张情况以及入院时胎膜是否膨出。还记录了就诊时是否存在临床症状或既往宫颈机能不全的危险因素。非连续性数据采用卡方检验或费舍尔精确检验进行分析;连续性数据采用学生t检验或曼-惠特尼U检验进行比较。

结果

环扎时的平均孕周为19.1±3.8周,宫内孕周增加的中位数为12周。总体而言,65%的患者在≥28周时分娩,49%的患者在≥34周时分娩。胎膜膨出的患者宫颈扩张>2 cm的可能性更大(58%对0%;p<0.001),且在孕周≥20周时就诊的可能性更大(69%对28%;p<0.001)。她们在环扎后孕周增加的时间也更少(中位数6.4周对17.0周;p<0.001),分娩时达到28周(44%对85%;p<0.001)或34周(31%对67%;p = 0.004)的可能性更小。

结论

就诊时胎膜膨出或宫颈扩张进展与环扎至分娩间隔时间缩短以及达到28周孕周的可能性降低有关。

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