Olatunbosun O A, al-Nuaim L, Turnell R W
Department of Obstetrics and Gynecology, University of Saskatchewan, Royal University Hospital, Saskatoon, Canada.
Int Surg. 1995 Apr-Jun;80(2):170-4.
In a cohort of 43 women with viable, singleton pregnancies, cervical dilatation greater than 4 cm, and absent labor between 20 and 27 weeks gestation, 22 women who underwent emergency cerclage within six hours of admission, were compared prospectively with 15 women who elected conservative bed rest treatment. The two groups were demographically similar. Emergency cervical cerclage resulted in a longer mean gestational age at delivery compared to bed rest (p = 0.001). Women treated with cerclage required a significantly shorter period of antepartum hospitalization (p = 0.001), required less tocolysis (p = 0.005), and experienced fewer preterm membrane ruptures compared to women in the bed rest group (p = 0.01), although the latency period, following preterm rupture of membranes was shorter in the cerclage group (p = 0.005). There was no statistical difference in the frequencies of chorioamnionitis, maternal morbidity and cesarean section between the two groups. Although the perinatal mortality in the two groups was not significantly different (p = 0.3), emergency cerclage resulted in a significantly higher mean birth weight compared to conservative bed rest treatment (p = 0.02). This study demonstrates the superiority of emergency cerclage to bed rest in women with advanced cervical dilatation and absent labor in late second-trimester of pregnancy.
在一组43例单胎活产妊娠、宫颈扩张大于4 cm且妊娠20至27周无宫缩的妇女中,对入院后6小时内接受急诊宫颈环扎术的22例妇女与选择保守卧床休息治疗的15例妇女进行了前瞻性比较。两组在人口统计学上相似。与卧床休息相比,急诊宫颈环扎术导致分娩时的平均孕周更长(p = 0.001)。与卧床休息组的妇女相比,接受环扎术治疗的妇女产前住院时间明显更短(p = 0.001),所需的宫缩抑制剂更少(p = 0.005),胎膜早破的情况也更少(p = 0.01),尽管环扎术组胎膜早破后的潜伏期更短(p = 0.005)。两组之间绒毛膜羊膜炎、孕产妇发病率和剖宫产的发生率没有统计学差异。虽然两组的围产儿死亡率没有显著差异(p = 0.3),但与保守卧床休息治疗相比,急诊宫颈环扎术导致平均出生体重显著更高(p = 0.02)。这项研究表明,对于妊娠晚期宫颈扩张且无宫缩的妇女,急诊宫颈环扎术优于卧床休息。