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前壁心肌梗死后室性心动过速的无标测大环状冷冻消融:长期结果

Large encircling cryoablation without mapping for ventricular tachycardia after anterior myocardial infarction: long-term outcome.

作者信息

Frapier J M, Hubaut J J, Pasquié J L, Chaptal P A

机构信息

Department of Cardiovascular Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.

出版信息

J Thorac Cardiovasc Surg. 1998 Oct;116(4):578-83. doi: 10.1016/S0022-5223(98)70163-1.

Abstract

OBJECTIVE

Map-guided procedures have been the accepted standard for ventricular tachycardia surgery. However, promising results of visually guided resections without mapping have been reported. The goal of this study was to evaluate the efficacy of large encircling cryoablation without mapping for ventricular tachycardia after anterior myocardial infarction.

METHODS

Between 1985 and 1996, this procedure, along with aneurysmectomy, was performed on 38 patients for malignant ventricular tachycardia. The mean interval between the operation and myocardial infarction was 59.2 months; 7 patients (18.4%) were operated on within 1 month of myocardial infarction. The mean patient age was 62.1 +/-7.3 years and the mean left ventricular ejection fraction was 29.0% +/-7.2%.

RESULTS

Hospital mortality was 2.6% (1 patient). The electrical success rate based on postoperative electrophysiologic studies was 94.5%. Overall electrical success rate was 89.1%. Freedom from ventricular tachycardia was 77% (95% CI 61%-94%) at both 5 and 7 years. Freedom from sudden cardiac death was 91% (95% CI 80%-100%) at both 5 and 7 years, with overall actuarial survivals at 5 and 7 years of 63% (95% CI 47%-80%) and 42% (95% CI 22%-63%), respectively. The main cause of late death was congestive heart failure in 62.6% of these patients.

CONCLUSIONS

One can achieve good results without intraoperative mapping in the treatment of patients with ventricular tachycardia after anterior myocardial infarction by using large encircling cryoablation.

摘要

目的

标测引导下的手术一直是室性心动过速手术的公认标准。然而,有报道称非标测直视下切除取得了令人鼓舞的结果。本研究的目的是评估大面积环形冷冻消融术在无前壁心肌梗死后室性心动过速标测情况下的疗效。

方法

1985年至1996年间,对38例恶性室性心动过速患者进行了该手术及动脉瘤切除术。手术与心肌梗死之间的平均间隔时间为59.2个月;7例患者(18.4%)在心肌梗死后1个月内接受了手术。患者平均年龄为62.1±7.3岁,平均左心室射血分数为29.0%±7.2%。

结果

医院死亡率为2.6%(1例患者)。根据术后电生理研究,电生理成功率为94.5%。总体电生理成功率为89.1%。5年和7年时无室性心动过速的发生率均为77%(95%可信区间61%-94%)。5年和7年时无心脏性猝死的发生率均为91%(95%可信区间80%-100%),5年和7年时的总体精算生存率分别为63%(95%可信区间47%-80%)和42%(95%可信区间22%-63%)。这些患者晚期死亡的主要原因是充血性心力衰竭,占62.6%。

结论

对于前壁心肌梗死后室性心动过速患者,采用大面积环形冷冻消融术,无需术中标测即可取得良好效果。

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