Cluff R S, Rowbotham M C
Department of Neurology, Pain Clinical Research Center, University of California, San Francisco 94115, USA.
Neurol Clin. 1998 Nov;16(4):813-32. doi: 10.1016/s0733-8619(05)70099-2.
Postherpetic neuralgia (PHN) is a neuropathic pain disorder that occurs most often in the elderly. This painful condition is uniquely suited for clinical research, resulting in an emerging understanding of the pathophysiology of the persistent pain. Until recently, only the tricyclic antidepressants proved effective for PHN. Controlled trials of a wide variety of therapeutic strategies are in progress or have been recently completed.
带状疱疹后神经痛（PHN）是一种最常发生于老年人的神经性疼痛疾病。这种疼痛状况特别适合进行临床研究，从而使人们对持续性疼痛的病理生理学有了新的认识。直到最近，只有三环类抗抑郁药被证明对PHN有效。各种治疗策略的对照试验正在进行或最近已经完成。
