巴西游走蛛毒素的胆碱能和肾上腺素能效应。
Cholinergic and adrenergic effects of tityustoxin.
作者信息
Freire-Maia L, Cunha-Melo J R, Futuro-Neto H A, Azevedo A D, Weinberg J
出版信息
Gen Pharmacol. 1976 Aug;7(2-3):115-21. doi: 10.1016/0306-3623(76)90046-x.
PMID:976730
Abstract
The effects of purified scorpion toxin (Tityustoxin or TsTX) were investigated on the isolated guinea-pig and rat ileum, rat spleen strip and hen rectal caecum. The contraction of the ileum was due only in part to the release of acetylcholine, whereas the contraction of the spleen strip and the relaxation of the rectal caecum were due to the release of catecholamines.
摘要
研究了纯化的蝎子毒素（Tityustoxin或TsTX）对离体豚鼠和大鼠回肠、大鼠脾脏条带以及母鸡直肠盲肠的作用。回肠的收缩仅部分归因于乙酰胆碱的释放，而脾脏条带的收缩和直肠盲肠的舒张则归因于儿茶酚胺的释放。
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