Pfitzenmeyer P, Lauwerier C, Camus A
Service de Médecine gériatrique, CHRU, Dijon.
Presse Med. 1998 May 16;27(18):878-83.
HIGH PREVALENCE: Several epidemiological studies have shown that the prevalence of bronchial asthma is high in the elderly. It is often difficult to establish the diagnosis of asthma in this population because of the scarcity of symptoms. Pulmonary function tests are widely used to confirm the diagnosis. These tests are possible in most elderly people excepting cases of severe dementia.
Pathophysiology of asthma in the elderly may be characterized by superimposition of different factors: 1) the effect of age which is associated with airway adrenoreceptor dysfunction; 2) the impact of chronic pulmonary diseases which may increase airways inflammation; 3) the role of triggers such as infections or various medications.
Management of asthma consists in a specific treatment of trigger(s) associated with anti-inflammatory and bronchodilator medications. Elderly subjects may have difficulty using offinhalators and spacer devices are widely used.
高患病率:多项流行病学研究表明,支气管哮喘在老年人中的患病率很高。由于症状稀少,在这一人群中往往难以确诊哮喘。肺功能测试被广泛用于确诊。除了严重痴呆病例外,大多数老年人都可以进行这些测试。
老年人哮喘的病理生理学可能具有不同因素叠加的特点:1)与气道肾上腺素能受体功能障碍相关的年龄影响;2)慢性肺部疾病的影响,这可能会加重气道炎症;3)感染或各种药物等触发因素的作用。
哮喘的管理包括对与抗炎和支气管扩张药物相关的触发因素进行特定治疗。老年患者使用定量吸入器可能有困难,因此广泛使用储物罐装置。