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[出血性直肠结肠炎行回肠肛管吻合加贮袋术后的袋炎]

[Pouchitis after ileo-anal anastomosis with a reservoir in hemorrhagic rectocolitis].

作者信息

Abitbol V, Chaussade S

机构信息

Service d'Hépato-Gastroentérologie, Hôpital Cochin, Paris.

出版信息

Presse Med. 1998 Mar 28;27(12):588-92.

PMID:9767957
Abstract

UNLABELLED

DEFINITION AND FREQUENCY: An ileoanal anastomosis with creation of an ideal pouch is proposed as the treatment for familial adenomatous polyposis and ulcerative hemorrhagic rectocolitis. The ideal pouch may become inflammatory in 10 to 30% of the cases. The diagnosis of pouchitis is based on a clinical, endoscopid and histological criteria.

PATHOGENIC HYPOTHESES

Pouchitis is a late complication, mainly after ileoanal anastomosis for ulcerative rectocolitis. The pathogenic mechanism is a subject of debate. Fecal stasis, bacterial pollution, mucine secretion and the underlying inflammatory disease could be involved.

TREATMENT

Antibiotics active against anaerobic bacteria, such as metronidazole, are generally given. In case of failure, common antiinflammatory agents used in inflammatory bowel disease are indicated.

摘要

未标注

定义与发生率:提议采用回肠肛管吻合术并构建理想储袋来治疗家族性腺瘤性息肉病和溃疡性出血性直肠结肠炎。理想储袋在10%至30%的病例中可能会发生炎症。储袋炎的诊断基于临床、内镜及组织学标准。

致病假说

储袋炎是一种晚期并发症,主要发生在溃疡性直肠结肠炎行回肠肛管吻合术后。致病机制存在争议。可能涉及粪便淤积、细菌污染、黏液分泌及潜在的炎症性疾病。

治疗

通常给予对厌氧菌有效的抗生素,如甲硝唑。若治疗失败,则使用炎症性肠病常用的抗炎药。

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